Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1054996 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TET2EGLN1TSHRKEAP1 | |
| SCHEMBL1164025 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TET2EGLN1TSHRKEAP1 | |
| SCHEMBL26039766 | 0.84 | — | — | |
| SCHEMBL10644664 | 0.84 | — | — | |
| SCHEMBL15133568 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TET2EGLN1TGFBR1 | |
| SCHEMBL28877364 | 0.82 | — | — | |
| SCHEMBL15131703 | 0.82 | — | — | |
| SCHEMBL9575126 | 0.79 | — | — | |
| SCHEMBL5352787 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TET2EGLN1TSHRKEAP1 | |
| SCHEMBL6950834 | 0.76 | ALDH1A1 (0.56) | ALDH1A1TET2EGLN1TSHRKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110004003-A1 | Compound, Photochromic Material, Electronic Material, Compound Producing Method, 2,3-BIS(N,N-BIS(P-ANISYL)4-Minophenylethynyl)Dimethylfumarate Producing Method and 2,3-BIS(N,N-BIS(P-ANISYL)4-Aminophenylethynyl)Dimethylmaleate Producing method | THE UNIVERSITY OF TOKYO (JP) | 2011-01-06 | — | — | US | claimed |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2021-03-02 | — | — | US | disclosed |
| US-20200108150-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | UCL BUSINESS LTD (GB) | 2020-04-09 | — | — | US | disclosed |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2020-02-04 | — | — | US | disclosed |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2019-05-16 | — | — | US | disclosed |
| US-10174094-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC (GB) | 2019-01-08 | — | — | US | disclosed |
| US-20160176942-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS PLC (GB) | 2016-06-23 | — | — | US | disclosed |
| US-9295729-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC (GB) | 2016-03-29 | — | — | US | disclosed |
| EP-2889624-A2 | Reversible covalent linkage of functional molecules | UCL Business PLC (GB) | 2015-07-01 | — | — | EP | disclosed |
| EP-2464654-B1 | THIOL PROTECTING GROUP | UCL BUSINESS PLC (GB) | 2014-10-08 | — | — | EP | disclosed |
| EP-2549276-A2 | Reversible covalent linkage of functional molecules | UCL Business PLC (GB) | 2013-01-23 | — | — | EP | disclosed |
| US-20120190579-A1 | Functionalisation of Solid Substrates | UCL BUSINESS PLC (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120190814-A1 | Thiol Protecting Group | UCL BUSINESS PLC (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2012-07-26 | — | — | US | disclosed |
| EP-2464972-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | UCL Business PLC (GB) | 2012-06-20 | — | — | EP | disclosed |
| EP-2464654-A2 | THIOL PROTECTING GROUP | UCL Business PLC (GB) | 2012-06-20 | — | — | EP | disclosed |
| EP-2464974-A1 | FUNCTIONALISATION OF SOLID SUBSTRATES | UCL Business PLC (GB) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011018613-A1 | FUNCTIONALISATION OF SOLID SUBSTRATES | UCL BUSINESS PLC (GB) | 2011-02-17 | — | — | WO | disclosed |
| WO-2011018611-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | UCL BUSINESS PLC (GB) | 2011-02-17 | — | — | WO | disclosed |
| WO-2011018612-A2 | THIOL PROTECTING GROUP | UCL BUSINESS PLC (GB) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004003-A1 | Compound, Photochromic Material, Electronic Material, Compound Producing Method, 2,3-BIS(N,N-BIS(P-ANISYL)4-Minophenylethynyl)Dimethylfumarate Producing Method and 2,3-BIS(N,N-BIS(P-ANISYL)4-Aminophenylethynyl)Dimethylmaleate Producing method | METTL14, DHPS, PAH | ALDH1A1 949/4885TET2 247/4885EGLN1 1338/4885 |
| US-10174094-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | ALDH1A1 76/4885TET2 2192/4885EGLN1 2897/4885 |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | ALDH1A1 76/4885TET2 2192/4885EGLN1 2897/4885 |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | ALDH1A1 76/4885TET2 2192/4885EGLN1 2897/4885 |
| US-20120190579-A1 | Functionalisation of Solid Substrates | XDH, SPR, DAO | ALDH1A1 3038/4885TET2 3531/4885EGLN1 2880/4885 |
| US-20160176942-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | ALDH1A1 76/4885TET2 2192/4885EGLN1 2897/4885 |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | ALDH1A1 76/4885TET2 2192/4885EGLN1 2897/4885 |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | ALDH1A1 76/4885TET2 2192/4885EGLN1 2897/4885 |
| US-20200108150-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | F12, F13A1, F2 | ALDH1A1 80/4885TET2 2203/4885EGLN1 2796/4885 |
| US-20120190814-A1 | Thiol Protecting Group | TXN, PRDX3, TST | ALDH1A1 118/4885TET2 671/4885EGLN1 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.