Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493845 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL361916 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GAAF2PRSS1PRSS2 | |
| Ammonia Solution, Strong SCHEMBL9252460 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL7319789 | 0.76 | ALDH1A1 (0.50) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL4119814 | 0.76 | ALDH1A1 (0.46) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL6283149 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL28003017 | 0.74 | ALDH1A1 (0.52) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL28887671 | 0.74 | ALDH1A1 (0.45) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL10637725 | 0.74 | ALDH1A1 (0.60) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL938973 | 0.73 | ALDH1A1 (0.46) | ALDH1A1GAAF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546587-B2 | Method for producing acrylate derivative, acrylate derivative, and intermediate thereof | KURARAY CO., LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8431722-B2 | Acrylate ester derivatives and polymer compounds | KURARAY CO., LTD. (JP) | 2013-04-30 | — | — | US | disclosed |
| US-8362169-B2 | Acrylate ester derivatives and polymer compounds | KURARAY CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20130005990-A1 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF | KURARAY CO., LTD. (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20120316349-A1 | ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS | KURARAY CO., LTD. (JP) | 2012-12-13 | — | — | US | disclosed |
| US-8314258-B2 | Method for producing acrylate derivative, acrylate derivative, and intermediate thereof | KURARAY CO., LTD. (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20110060112-A1 | ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS | KURARAY CO., LTD. (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20110009643-A1 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF | KURARAY CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005990-A1 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF | ACR, ADH1A, ALAD | ALDH1A1 13/4885GAA 3265/4885F2 1473/4885 |
| US-20120316349-A1 | ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS | ADH1A, ADH1C, ADH5 | ALDH1A1 7/4885GAA 4687/4885F2 1743/4885 |
| US-20110060112-A1 | ACRYLATE ESTER DERIVATIVES AND POLYMER COMPOUNDS | RAD51, LBR, RPLP0 | ALDH1A1 2980/4885GAA 3061/4885F2 4077/4885 |
| US-20110009643-A1 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF | ACR, ADH1A, ALAD | ALDH1A1 13/4885GAA 3265/4885F2 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.