Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547136 | 0.88 | ALDH1A1 (0.48) | ALDH1A1BCHEACHEKMT2AMEN1 | |
| SCHEMBL10548744 | 0.80 | MLYCD (0.48) | ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL10544853 | 0.77 | ALDH1A1 (0.45) | ALDH1A1BCHEACHEKMT2AMEN1 | |
| SCHEMBL10546095 | 0.71 | KMT2A (0.44) | ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL10546564 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1LMNAHSP90AA1 | |
| SCHEMBL10547048 | 0.68 | TP53 (0.48) | ALDH1A1LMNATP53 | |
| SCHEMBL10546055 | 0.67 | MLYCD (0.51) | ALDH1A1KMT2ALMNA | |
| SCHEMBL10546758 | 0.67 | RIPK1 (0.51) | ALDH1A1KMT2AMEN1LMNAHSD17B1 | |
| SCHEMBL9149586 | 0.65 | THRA (0.54) | KMT2ATHRATHRBLMNA | |
| SCHEMBL13381405 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1USP2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814341-A | HISTAMINE H2 ANTAGONISTS | REITER LAWRENCE A (US) | 1989-03-21 | — | — | US | disclosed |