Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575981 | 0.92 | AMY1A (0.31) | HDAC6F9F11F7AMY1A | |
| SCHEMBL10578009 | 0.87 | THRB (0.36) | HDAC6AMY1AF2F10PLG | |
| SCHEMBL10578367 | 0.82 | AMY1A (0.36) | HDAC6AMY1ATRPV1TP53HRH4 | |
| SCHEMBL10574094 | 0.82 | DGAT1 (0.44) | HDAC6TRPV1DGAT1KCNH2MAPT | |
| SCHEMBL10580112 | 0.81 | PDE5A (0.47) | HDAC6AMY1AF2F10PLG | |
| SCHEMBL10574102 | 0.81 | AMY1A (0.50) | AMY1AHRH4 | |
| SCHEMBL10577231 | 0.80 | AMY1A (0.55) | HDAC6AMY1ATRPV1DGAT1KCNH2 | |
| SCHEMBL10579371 | 0.80 | CDK4 (0.44) | AMY1ASCD | |
| SCHEMBL10578002 | 0.79 | AMY1A (0.32) | HDAC6AMY1A | |
| SCHEMBL10574279 | 0.79 | SLC2A1 (0.55) | TRPV1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |