SCHEMBL106159

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL110056	0.95	POLB (0.46)	POLBCNR2CES2CES1CA2
	SCHEMBL105011	0.90	CYP3A4 (0.39)	POLBCES2CES1SMN1; SMN2CYP3A4
	SCHEMBL105612	0.85	PPARG (0.41)	POLBCES2CES1TDP1SMN1; SMN2
	Ethylmalonate SCHEMBL107811	0.83	MEN1 (0.45)	POLBCES2CES1ALDH1A1MEN1
	Ethylmalonate SCHEMBL110047	0.81	MEN1 (0.40)	POLBCES2CES1ALDH1A1MEN1
	SCHEMBL105351	0.81	POLB (0.47)	POLBCNR2CES2CES1CA2
	Valeric Acid SCHEMBL106459	0.78	CA1 (0.55)	CES2CES1MEN1KMT2ACA1
	Hexanoate SCHEMBL105634	0.77	CES2 (0.53)	CES2CES1CA1
	Potassium Ion SCHEMBL108612	0.76	CA2 (0.56)	CES2CES1CA2MAPK1CYP3A4
	SCHEMBL21269384	0.76	CA2 (0.56)	CES2CES1CA2MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.