Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064254 | 0.83 | ADORA2A (0.38) | ASIC3ADORA2AKDM4CDYRK1AADORA1 | |
| SCHEMBL1062624 | 0.75 | DYRK1A (0.44) | ADORA2ADYRK1AADORA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1062470 | 0.72 | TDO2 (0.46) | ADORA2AKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL1059268 | 0.72 | MAP4K4 (0.45) | ADORA2ADYRK1ACFDKDM4EALDH1A1 | |
| SCHEMBL1062365 | 0.71 | ADORA2A (0.38) | ADORA2ADYRK1AADORA1CFDATM | |
| SCHEMBL4361201 | 0.70 | ASIC3 (0.57) | ASIC3KDM4CTP53SMN1; SMN2KDM4E | |
| SCHEMBL314105 | 0.70 | ASIC3 (0.67) | ASIC3KDM4CTP53SMN1; SMN2KDM4E | |
| SCHEMBL7089309 | 0.70 | ASIC3 (0.52) | ASIC3KDM4CKDM1ATP53SMN1; SMN2 | |
| SCHEMBL2274975 | 0.69 | MAOA (0.39) | ADORA2ADYRK1AADORA1ALDH1A1TSHR | |
| SCHEMBL18152703 | 0.68 | ADORA2A (0.35) | ADORA2AADORA1CFDTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015185-A1 | Benzofuran Compounds | BIOVITRUM AB (SE) | 2011-01-20 | — | — | US | disclosed |
| US-7820675-B2 | Benzofuran compounds | BIOVITRUM AB (SE) | 2010-10-26 | — | — | US | disclosed |
| US-20060287291-A1 | Compounds | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287291-A1 | Compounds | HTR6, HTR1B, HTR1A | ASIC3 1467/4885ADORA2A 38/4885KDM4C 3618/4885 |
| US-20110015185-A1 | Benzofuran Compounds | HTR6, HTR1F, HTR1A | ASIC3 1762/4885ADORA2A 108/4885KDM4C 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.