Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL7651538 | 0.88 | PTGS1 (0.53) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL21777928 | 0.88 | PTGS1 (0.60) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2058760 | 0.88 | CA5A (0.46) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL126970 | 0.88 | — | — | |
| SCHEMBL2622 | 0.88 | PTGS1 (0.60) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL1904 | 0.88 | — | — | |
| SCHEMBL8768770 | 0.86 | LMNA (0.45) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Methyl Alcohol SCHEMBL23421569 | 0.84 | — | — | |
| SCHEMBL22581624 | 0.84 | — | — | |
| SCHEMBL20533683 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158339-A1 | TYRAMINE CONTAINING HYDROXYCINNAMIC ACID AMIDE DERIVATIVES AND METHODS OF USE THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2024-05-16 | — | — | US | disclosed |
| EP-3288548-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | Parion Sciences, Inc. (US) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016176423-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-11-03 | — | — | WO | disclosed |
| US-20150307530-A1 | NOVEL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2015-10-29 | — | — | US | disclosed |
| US-7863286-B2 | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-20070179140-A1 | Stereoisomerically Enriched 3-Aminocarbonyl Bicycloheptene Pyrimidinediamine Compounds And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307530-A1 | NOVEL MUCOLYTIC AGENTS | MUC1, MMP8, MMP7 | PTGS1 402/4885PDE4A 127/4885LMNA 4248/4885 |
| US-20070179140-A1 | Stereoisomerically Enriched 3-Aminocarbonyl Bicycloheptene Pyrimidinediamine Compounds And Their Uses | MKI67, PCNA, CCNI | PTGS1 1882/4885PDE4A 2948/4885LMNA 3220/4885 |
| US-20240158339-A1 | TYRAMINE CONTAINING HYDROXYCINNAMIC ACID AMIDE DERIVATIVES AND METHODS OF USE THEREOF | GLS2, LIPC, AADAT | PTGS1 2165/4885PDE4A 3160/4885LMNA 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.