Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26638 | 1.00 | SIGMAR1 (0.33) | SIGMAR1LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL2160342 | 1.00 | SIGMAR1 (0.33) | SIGMAR1LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL3649223 | 1.00 | SIGMAR1 (0.33) | SIGMAR1LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL5595562 | 1.00 | SIGMAR1 (0.33) | SIGMAR1LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL16442927 | 0.69 | CTDSP1 (0.34) | SIGMAR1LMNAAPOBEC3ACTDSP1APOBEC3G | |
| SCHEMBL25280948 | 0.65 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL4582773 | 0.60 | — | — | |
| SCHEMBL17048819 | 0.58 | — | — | |
| SCHEMBL494491 | 0.58 | — | — | |
| SCHEMBL1031219 | 0.58 | CTDSP1 (0.50) | SIGMAR1LMNAMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767286-B2 | Phenylpropionate compound, preparation method for same, and applications thereof | SUZHOU PHARMAVAN CO., LTD (CN) | 2023-09-26 | — | — | US | claimed |
| CN-108084030-B | Phenylpropanoid ester compound and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-108047048-B | Phenylpropanoate compound and preparation method and application thereof | 苏州沪云肿瘤研究中心股份有限公司 | 2021-01-12 | — | — | CN | claimed |
| EP-3733640-A1 | PHENYLPROPIONATE COMPOUND, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF | Suzhou Pharmavan Co., Ltd. (CN) | 2020-11-04 | — | — | EP | claimed |
| US-20200331842-A1 | PHENYLPROPIONATE COMPOUND, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF | SUZHOU PHARMAVAN CO., LTD (CN) | 2020-10-22 | — | — | US | claimed |
| US-20140357614-A1 | Diamino-Pyridine, Pyrimidine, and Pyrazine Modulators of the Histamine H4 Receptor | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-04 | — | — | US | claimed |
| US-8841287-B2 | Diamino-pyridine, pyrimidine, and pyrazine modulators of the histamine H4 receptor | JANSSEN PHARMACEUTICA N.V. (BE) | 2014-09-23 | — | — | US | claimed |
| EP-2315521-B1 | DIAMINO-PYRIDINE, PYRIMIDINE, AND PYRIDAZINE MODULATORS OF THE HISTAMINE H 4 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2014-05-21 | — | — | EP | claimed |
| EP-2280965-B1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-08-29 | — | — | EP | claimed |
| US-20110092474-A1 | Diamino-pyridine, pyrimidine, and pyrazine modulators of the histamine H4 receptor | JANSSEN PHARMACEUTICA NV | 2011-04-21 | — | — | US | claimed |
| EP-2207766-A1 | NOVEL SULFAMATE COMPOUNDS FOR MEDICAL USE | Abbott Products GmbH (DE) | 2010-07-21 | — | — | EP | claimed |
| EP-2203427-A2 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLES AS CANNABINOID CB1 RECEPTOR AGONISTS | Abbott Healthcare Products B.V. (NL) | 2010-07-07 | — | — | EP | claimed |
| US-7579335-B2 | Androstane 17α-carbonate derivatives for use in the treatment of allergic and inflammatory conditions | GLAXO GROUP LIMITED (GB) | 2009-08-25 | — | — | US | claimed |
| US-20090104126-A1 | Sulfamate Compounds and Uses Thereof | SOLVAY PHARMACEUTICALS GMBH (DE) | 2009-04-23 | — | — | US | claimed |
| WO-2009050252-A1 | NOVEL SULFAMATE COMPOUNDS FOR MEDICAL USE | SOLVAY PHARMACEUTICALS GMBH (DE) | 2009-04-23 | — | — | WO | claimed |
| WO-2009037244-A2 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLES AS CANNABINOID CB1 RECEPTOR AGONISTS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2009-03-26 | — | — | WO | claimed |
| US-20090082396-A1 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLINES AS CANNABINOID CB1 RECEPTOR AGONISTS | SOLVAY PHARMACEUTICALS B.V. | 2009-03-26 | — | — | US | claimed |
| US-20080182831-A1 | Androstane 17-Alpha Carbonate Derivatives for Use in the Treatment of Allergic and Inflammatory Conditions | GLAXO GROUP LIMITED | 2008-07-31 | — | — | US | claimed |
| EP-1841780-A2 | ANDROSTANE 17-ALPHA-CARBONATE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC AND INFLAMMATORY CONDITIONS | GLAXO GROUP LIMITED (GB) | 2007-10-10 | — | — | EP | claimed |
| WO-2006072599-A2 | ANDROSTANE 17-ALPHA CARBONATE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC AND INFLAMMATORY CONDITIONS | GLAXO GROUP LIMITED (GB) | 2006-07-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767286-B2 | Phenylpropionate compound, preparation method for same, and applications thereof | PLAT, TFPI, PF4 | SIGMAR1 3060/4885LMNA 2705/4885MAPT 44/4885 |
| US-20080182831-A1 | Androstane 17-Alpha Carbonate Derivatives for Use in the Treatment of Allergic and Inflammatory Conditions | CYP11B1, CYP17A1, HSD3B1 | SIGMAR1 1006/4885LMNA 2267/4885MAPT 2852/4885 |
| US-20200331842-A1 | PHENYLPROPIONATE COMPOUND, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF | PLAT, TFPI, PF4 | SIGMAR1 3060/4885LMNA 2705/4885MAPT 44/4885 |
| US-20090082396-A1 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLINES AS CANNABINOID CB1 RECEPTOR AGONISTS | CNR1, CNR2, HTR5A | SIGMAR1 233/4885LMNA 4219/4885MAPT 3215/4885 |
| US-20110092474-A1 | Diamino-pyridine, pyrimidine, and pyrazine modulators of the histamine H4 receptor | HRH4, HRH3, HRH2 | SIGMAR1 1373/4885LMNA 4851/4885MAPT 1317/4885 |
| US-20090104126-A1 | Sulfamate Compounds and Uses Thereof | SULT1A1, SULT1E1, SULT2A1 | SIGMAR1 1699/4885LMNA 3434/4885MAPT 3305/4885 |
| US-20140357614-A1 | Diamino-Pyridine, Pyrimidine, and Pyrazine Modulators of the Histamine H4 Receptor | HRH4, HRH3, HRH2 | SIGMAR1 1373/4885LMNA 4851/4885MAPT 1317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.