Sugi Predict

Sugi Predict / Compounds / SCHEMBL2160342

SCHEMBL2160342

SCHEMBL2160342

CC1(C)C2C[CH][C@]1(C)CC2

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 4/20 0.33
▸ LMNA P02545 2/20 0.31
▸ MAPT P10636 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ APOBEC3A P31941 1/20 0.31
▸ CTDSP1 Q9GZU7 1/20 0.31
▸ APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1067931 1.00 SIGMAR1 (0.33) SIGMAR1LMNAMAPTMEN1ALDH1A1
SCHEMBL26638 1.00 SIGMAR1 (0.33) SIGMAR1LMNAMAPTMEN1ALDH1A1
SCHEMBL3649223 1.00 SIGMAR1 (0.33) SIGMAR1LMNAMAPTMEN1ALDH1A1
SCHEMBL5595562 1.00 SIGMAR1 (0.33) SIGMAR1LMNAMAPTMEN1ALDH1A1
SCHEMBL16442927 0.69 CTDSP1 (0.34) SIGMAR1LMNAAPOBEC3ACTDSP1APOBEC3G
SCHEMBL25280948 0.65 SIGMAR1 (0.31) SIGMAR1
SCHEMBL4582773 0.60 — —
SCHEMBL17048819 0.58 — —
SCHEMBL494491 0.58 — —
SCHEMBL1031219 0.58 CTDSP1 (0.50) SIGMAR1LMNAMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101353313-A Process to produce oxazolidinones UPJOHN CO (US) 2009-01-28 — — CN claimed
EP-1028940-B1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN CO LLC (US) 2007-04-18 — — EP claimed
EP-1772453-A1 Process to produce Oxazolidinones Pharmacia & Upjohn Company LLC (US) 2007-04-11 — — EP claimed
US-6740754-B2 CYCLIZATION OF CARBAMATE WITH SECONDARY ALCOHOL, EPOXIDE OR ESTER REACTANT PHARMACIA & UPJOHN COMPANY 2004-05-25 — — US claimed
US-6716980-B2 CYCLIZATION AND ACYLATION OF CARBAMATE PHARMACIA & UPJOHN COMPANY 2004-04-06 — — US claimed
US-20040006238-A1 Process to produce oxazolidinones PHARMACIA & UPJOHN COMPANY 2004-01-08 — — US claimed
US-20030216572-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY 2003-11-20 — — US claimed
US-20030130509-A1 PROCESS TO PRODUCE 3-CARBON AMINO ALCOHOL SALTS PHARMACIA & UPJOHN COMPANY 2003-07-10 — — US claimed
US-20030065219-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY 2003-04-03 — — US claimed
EP-1107947-B1 METHOD FOR PRODUCING CYANOVALERIC ACID OR ESTERS THEREOF BASF AG (DE) 2003-01-08 — — EP claimed
US-6492323-B2 CONTROLLED RELEASE UPON EXPOSURE TO LIGHT FIRMENICH SA (CH) 2002-12-10 — — US claimed
US-6492555-B2 REACTION OF A CARBAMATE WITH EITHER A (S)-SECONDARY ALCOHOL OR (S)-EPOXIDE OR (S)-ESTER; BACTERICIDES PHARMACIA & UPJOHN COMPANY 2002-12-10 — — US claimed
US-20020095054-A1 Process to produce oxazolidinones PHARMACIA & UPJOHN COMPANY 2002-07-18 — — US claimed
US-20020032348-A1 Process to produce oxazolidinones PEARLMAN BRUCE ALLEN (US) 2002-03-14 — — US claimed
CN-1275122-A Process for preparing oxazolidinones UPJOHN CO (US) 2000-11-29 — — CN claimed
EP-1028940-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 2000-08-23 — — EP claimed
WO-1999024393-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 1999-05-20 — — WO claimed
US-11744785-B2 Use of volatile compositions to limit or eliminate the perception of malodor FIRMENICH SA (CH) 2023-09-05 — — US disclosed
US-6346640-B1 REACTION OF PENTENENITRILE WITH CARBON MONOXIDE AND HYDROXY COMPOUNDS IN THE PRESENCE OF CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 2002-02-12 — — US disclosed
US-6218355-B1 FOR RELEASING FRAGRANT COMPOUND OR COMPOUNDS IN A CONTROLLED MANNER, MAINTAINING A DESIRED SMELL OVER A PROLONGED PERIOD OF TIME FIRMENICH SA (CH) 2001-04-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065219-A1 PROCESS TO PRODUCE OXAZOLIDINONES ADH1A, ADH5, ADH1C SIGMAR1 292/4885LMNA 2707/4885MAPT 3538/4885
US-11744785-B2 Use of volatile compositions to limit or eliminate the perception of malodor TAS2R8, TRPA1, TAS2R10 SIGMAR1 16/4885LMNA 3892/4885MAPT 2487/4885
US-20030130509-A1 PROCESS TO PRODUCE 3-CARBON AMINO ALCOHOL SALTS ADH1A, ADH5, ADH1C SIGMAR1 203/4885LMNA 3240/4885MAPT 3318/4885
US-20040006238-A1 Process to produce oxazolidinones ADH1A, ADH5, ADH1C SIGMAR1 282/4885LMNA 2704/4885MAPT 3496/4885
US-20020095054-A1 Process to produce oxazolidinones ADH1A, ADH5, ADH1C SIGMAR1 292/4885LMNA 2707/4885MAPT 3538/4885
US-20030216572-A1 PROCESS TO PRODUCE OXAZOLIDINONES ADH1A, ADH5, ADH1C SIGMAR1 292/4885LMNA 2707/4885MAPT 3538/4885
US-20020032348-A1 Process to produce oxazolidinones ADH1A, ADH5, ADH1C SIGMAR1 292/4885LMNA 2707/4885MAPT 3538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.