Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683067 | 0.89 | KDM4E (0.37) | DRD2TRPA1CYP3A4TMIGD3ADORA1 | |
| SCHEMBL10680981 | 0.86 | DRD2 (0.38) | CDC7DRD2TRPA1CYP3A4TMIGD3 | |
| SCHEMBL10680809 | 0.85 | DRD2 (0.36) | CDC7DRD2TRPA1CYP3A4TMIGD3 | |
| SCHEMBL10675710 | 0.84 | ALDH1A1 (0.51) | PDE3BPDE3AALDH1A1LMNAMAPT | |
| SCHEMBL10681929 | 0.81 | CDC7 (0.42) | CDC7CYP3A4PDE3BPDE3AALDH1A1 | |
| SCHEMBL10676837 | 0.81 | CDC7 (0.42) | CDC7ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL7376126 | 0.81 | PDE3B (0.44) | DRD2TRPA1PDE3BPDE3AALDH1A1 | |
| SCHEMBL10678289 | 0.80 | CDC7 (0.56) | CDC7PDE3BPDE3ACHEK2 | |
| SCHEMBL10675744 | 0.78 | DRD2 (0.38) | CDC7DRD2TRPA1CYP3A4ADORA1 | |
| SCHEMBL10679788 | 0.78 | MAPT (0.49) | CDC7ALDH1A1MAPTCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |