Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683067 | 0.86 | KDM4E (0.37) | DRD2TRPA1CYP3A4TMIGD3ADORA1 | |
| SCHEMBL10680981 | 0.86 | DRD2 (0.38) | DRD2TRPA1CYP3A4TMIGD3ADORA1 | |
| SCHEMBL10684915 | 0.85 | CDC7 (0.40) | DRD2TRPA1CYP3A4TMIGD3ADORA1 | |
| SCHEMBL10675710 | 0.84 | ALDH1A1 (0.51) | PDE3BPDE3AKDM4EGAACDK5 | |
| SCHEMBL7376126 | 0.83 | PDE3B (0.44) | DRD2TRPA1PDE3BPDE3AKDM4E | |
| SCHEMBL10677717 | 0.82 | ALDH1A1 (0.44) | PDE3BPDE3AGAAHPGDLMNA | |
| SCHEMBL10675744 | 0.80 | DRD2 (0.38) | DRD2TRPA1CYP3A4PDE4APDE4B | |
| SCHEMBL10678457 | 0.78 | LMNA (0.40) | CYP3A4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10681806 | 0.78 | PDE3B (0.55) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL10682046 | 0.76 | MAPT (0.48) | KDM4EGAAHPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |