Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691473 | 0.90 | RIPK1 (0.53) | ALDH1A1LMNAGAAHPGDCYP2C9 | |
| SCHEMBL10694465 | 0.88 | SMN1; SMN2 (0.54) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL10693248 | 0.87 | TAAR1 (0.49) | MEN1KMT2ACYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL10692204 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2ACYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL10693154 | 0.86 | NPC1 (0.54) | MEN1KMT2ACYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL10694507 | 0.79 | CNR1 (0.40) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL10690915 | 0.77 | MEN1 (0.54) | MEN1KMT2ACYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL9501899 | 0.77 | MMP8 (0.50) | CYP2C19CYP1A2ALDH1A1PLAAT5PLAAT4 | |
| SCHEMBL10692779 | 0.75 | POLB (0.61) | KMT2ACYP2C19GAAHPGDL3MBTL1 | |
| SCHEMBL10692590 | 0.74 | ALDH1A1 (0.42) | CYP1A2ALDH1A1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |