Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691473 | 0.89 | RIPK1 (0.53) | RAB9AALDH1A1CYP2C9HPGD | |
| SCHEMBL10693892 | 0.88 | SMN1; SMN2 (0.57) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL10694465 | 0.87 | SMN1; SMN2 (0.54) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL10692204 | 0.86 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL10692252 | 0.86 | MEN1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL13569360 | 0.82 | NPC1 (0.61) | NPC1RAB9ACASRALDH1A1MEN1 | |
| SCHEMBL10690147 | 0.81 | NPC1 (0.59) | NPC1RAB9ACASRALDH1A1MEN1 | |
| SCHEMBL10694507 | 0.78 | CNR1 (0.40) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL744864 | 0.76 | NPC1 (0.59) | NPC1RAB9ACASRALDH1A1MEN1 | |
| SCHEMBL9501899 | 0.76 | MMP8 (0.50) | NPC1RAB9AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |