Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691415 | 0.80 | DRD2 (0.44) | DRD2ADRA1AMAPTADRA2AADRA2B | |
| SCHEMBL10694700 | 0.79 | DRD2 (0.39) | DRD2DRD4ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL10690626 | 0.77 | HTR1A (0.45) | DRD2ADRA1ALMNAHTR2AALDH1A1 | |
| SCHEMBL10688450 | 0.72 | ADRA1A (0.46) | DRD2DRD4ADRA1AADRA1DADRA1B | |
| SCHEMBL10690584 | 0.70 | ALDH1A1 (0.36) | DRD2ADRA1AADRA1DADRA1BMAPT | |
| SCHEMBL30489285 | 0.69 | TSHR (0.65) | DRD2DRD4ADRA1AADRA1DADRA1B | |
| SCHEMBL10695532 | 0.69 | TSHR (0.65) | DRD2DRD4ADRA1AADRA1DADRA1B | |
| SCHEMBL10855051 | 0.68 | BRD4 (0.33) | LMNAMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL27267555 | 0.68 | TP53 (0.31) | TP53ALDH1A1KDM4ETDP1GAA | |
| SCHEMBL10694109 | 0.68 | POLB (0.35) | DRD2ADRA1AADRA1DADRA1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |