Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718340 | 0.87 | ALDH1A1 (0.41) | EPHX2MMP3MMP1MMP2EPHX1 | |
| SCHEMBL10717336 | 0.71 | ALDH1A1 (0.42) | EPHX2EPHX1ALDH1A1RECQL | |
| SCHEMBL7546570 | 0.71 | MMP1 (0.39) | MMP1MMP2 | |
| SCHEMBL10716186 | 0.69 | CTSK (0.48) | MMP3MMP1MMP2ACE2 | |
| SCHEMBL10716135 | 0.68 | MMP3 (0.51) | EPHX2MMP3MMP1MMP2ACE2 | |
| SCHEMBL7506441 | 0.67 | PPARA (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL1559847 | 0.67 | SIGMAR1 (0.45) | TAAR1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL1559846 | 0.67 | SIGMAR1 (0.45) | TAAR1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9505541 | 0.67 | EPHX2 (0.58) | EPHX2TAAR1SMN1; SMN2EPHX1NPC1 | |
| SCHEMBL10717483 | 0.66 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |