Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 4/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 3/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739775 | 0.82 | ALKBH2 (0.63) | ALKBH2ALKBH3FTOKAT6AALKBH5 | |
| SCHEMBL8869169 | 0.81 | ALKBH2 (0.54) | ALKBH2ALKBH3FTOKAT6AALKBH5 | |
| SCHEMBL8997269 | 0.79 | FLT1 (0.60) | AGTR2AGTR1BCL2L1MCL1CASP1 | |
| SCHEMBL7867915 | 0.79 | ALKBH2 (0.40) | ALKBH2ALKBH3FTOKAT6AALKBH5 | |
| SCHEMBL8868423 | 0.77 | ALKBH2 (0.52) | ALKBH2ALKBH3FTOALKBH5 | |
| SCHEMBL18921577 | 0.74 | PTGS2 (0.60) | AGTR2AGTR1EDNRBEDNRA | |
| SCHEMBL9515762 | 0.73 | P4HTM (0.49) | AGTR2AGTR1CASP1 | |
| SCHEMBL8869193 | 0.72 | P4HTM (0.54) | AGTR2AGTR1 | |
| SCHEMBL8240985 | 0.72 | CASP1 (0.56) | BCL2L1MCL1CASP1EDNRBEDNRA | |
| SCHEMBL10740058 | 0.72 | PTGS2 (0.66) | ALKBH2ALKBH3FTOALKBH5BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4690934-A | N-phenylsulfonylisonicotinamide derivatives and their use as fungicides or bactericides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-09-01 | — | — | US | disclosed |