Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 4/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869169 | 0.85 | GABRA5 (0.44) | AGTR2AGTR1 | |
| SCHEMBL8869169 | 0.85 | ALKBH2 (0.54) | ALKBH2ALKBH3FEN1FTOKAT6A | |
| SCHEMBL9574709 | 0.84 | FEN1 (0.40) | FEN1ALOX5AP | |
| SCHEMBL10738335 | 0.79 | ALKBH2 (0.47) | ALKBH2ALKBH3FTOKAT6AAGTR2 | |
| SCHEMBL8868423 | 0.77 | ALKBH2 (0.52) | ALKBH2ALKBH3FTOALKBH5 | |
| SCHEMBL8869193 | 0.75 | P4HTM (0.54) | AGTR2AGTR1 | |
| SCHEMBL9574694 | 0.75 | MEN1 (0.47) | FEN1ALOX5AP | |
| SCHEMBL9574760 | 0.75 | ALDH1A1 (0.39) | AGTR2 | |
| SCHEMBL7867676 | 0.74 | EPHX2 (0.42) | ALKBH2ALKBH3FTOALKBH5 | |
| SCHEMBL7869455 | 0.71 | P4HTM (0.57) | ALKBH2FTOALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |