Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 3/20 | 0.63 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.63 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.58 |
| ▸ | FLT1 | P17948 | 4/20 | 0.56 |
| ▸ | FLT4 | P35916 | 4/20 | 0.56 |
| ▸ | KDR | P35968 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740984 | 0.86 | PTGS2 (0.55) | ALKBH2FTOALKBH5PTGS2PTGS1 | |
| SCHEMBL10740058 | 0.86 | PTGS2 (0.66) | ALKBH2FTOALKBH5PTGS2PTGS1 | |
| SCHEMBL10744485 | 0.84 | PTGS2 (0.63) | ALKBH2FTOALKBH5PTGS2PTGS1 | |
| SCHEMBL10738335 | 0.82 | ALKBH2 (0.47) | ALKBH2FTOALKBH5KAT6AALKBH3 | |
| SCHEMBL7691939 | 0.79 | P4HTM (0.52) | ALKBH2FTOALKBH5PTGS2PTGS1 | |
| SCHEMBL10746411 | 0.79 | PTGS2 (0.71) | ALKBH2FTOALKBH5PTGS2PTGS1 | |
| SCHEMBL174010 | 0.76 | FLT1 (0.77) | PTGS2PTGS1FLT1FLT4KDR | |
| SCHEMBL5931288 | 0.76 | FLT1 (0.71) | PTGS2PTGS1FLT1FLT4KDR | |
| SCHEMBL736261 | 0.76 | LMNA (0.62) | — | |
| SCHEMBL9519602 | 0.75 | ALKBH2 (0.53) | ALKBH2FTOALKBH5PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4690934-A | N-phenylsulfonylisonicotinamide derivatives and their use as fungicides or bactericides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-09-01 | — | — | US | disclosed |
| CN-86106552-A | N-benzenesulfonyl Isonicotinamide derivative and they purposes as mycocide and sterilant | — | 1987-05-27 | — | — | CN | disclosed |