Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.55 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | FLT1 | P17948 | 6/20 | 0.50 |
| ▸ | FLT4 | P35916 | 6/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.50 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CCR9 | P51686 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740058 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL10739775 | 0.86 | ALKBH2 (0.63) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL5743063 | 0.73 | TAS1R3 (0.55) | — | |
| SCHEMBL10738335 | 0.72 | ALKBH2 (0.47) | ALKBH2ALKBH5FTOALKBH3 | |
| SCHEMBL3993358 | 0.71 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL580761 | 0.71 | PTGS2 (0.41) | PTGS2L3MBTL1CCR9 | |
| SCHEMBL15625450 | 0.71 | PKM (0.51) | PTGS2PTGS1 | |
| SCHEMBL6883165 | 0.70 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL30700822 | 0.70 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL10621867 | 0.70 | FLT1 (0.54) | PTGS2PTGS1EGFRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4690934-A | N-phenylsulfonylisonicotinamide derivatives and their use as fungicides or bactericides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-09-01 | — | — | US | disclosed |
| CN-86106552-A | N-benzenesulfonyl Isonicotinamide derivative and they purposes as mycocide and sterilant | — | 1987-05-27 | — | — | CN | disclosed |