Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 7/20 | 0.54 |
| ▸ | FLT4 | P35916 | 7/20 | 0.54 |
| ▸ | KDR | P35968 | 7/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740058 | 0.76 | PTGS2 (0.66) | FLT1FLT4KDRPTGS2PTGS1 | |
| SCHEMBL10739775 | 0.72 | ALKBH2 (0.63) | FLT1FLT4KDRPTGS2PTGS1 | |
| SCHEMBL10740984 | 0.70 | PTGS2 (0.55) | FLT1FLT4KDRPTGS2PTGS1 | |
| SCHEMBL2997667 | 0.70 | KDM4E (0.55) | L3MBTL1CYP3A4 | |
| SCHEMBL13702396 | 0.70 | TAS1R3 (0.55) | — | |
| SCHEMBL31082091 | 0.70 | TAS1R3 (0.55) | — | |
| SCHEMBL21999900 | 0.68 | ACLY (0.70) | FLT1FLT4KDR | |
| SCHEMBL3569008 | 0.67 | TAS1R3 (0.44) | ALKBH5FTO | |
| SCHEMBL12242738 | 0.67 | FLT1 (0.64) | FLT1FLT4KDRPTGS2PTGS1 | |
| SCHEMBL13702293 | 0.66 | TAS1R3 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63057570-A | — | — | None | — | — | JP | disclosed |
| JP-S6357570-A | N-PHENYLSULFONYLISONICOTINAMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE COMPOSITION CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | NIPPON KAYAKU CO LTD | 1988-03-12 | — | — | JP | disclosed |