Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPIB | P23284 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | PPIG | Q13427 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749977 | 0.84 | MC4R (0.44) | TDP1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10972161 | 0.80 | USP2 (0.40) | TDP1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL10753221 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL10752287 | 0.79 | MEN1 (0.44) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL10752292 | 0.77 | HDAC6 (0.37) | TDP1ALDH1A1KDM4ELMNAHDAC1 | |
| SCHEMBL10757418 | 0.74 | LMNA (0.39) | ITGB3ITGAVTDP1ALDH1A1KDM4E | |
| SCHEMBL18068879 | 0.69 | CETP (0.43) | ITGB3ITGAVTDP1MAPTALDH1A1 | |
| SCHEMBL24073242 | 0.69 | ALDH1A1 (0.46) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL1351101 | 0.68 | TSHR (0.48) | TSHR | |
| SCHEMBL10531431 | 0.68 | MAPT (0.47) | ITGB3ITGAVMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |