Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973111 | 0.85 | HDAC6 (0.39) | HDAC6TDP1OPRM1OPRD1ALDH1A1 | |
| SCHEMBL10752287 | 0.79 | MEN1 (0.44) | LMNA | |
| SCHEMBL10757422 | 0.77 | ITGB3 (0.37) | HDAC6TDP1PTGESALDH1A1KDM4E | |
| SCHEMBL10749977 | 0.74 | MC4R (0.44) | TDP1ALDH1A1LMNA | |
| SCHEMBL10753221 | 0.74 | ALDH1A1 (0.48) | ALDH1A1LMNA | |
| SCHEMBL7304372 | 0.68 | CYP1A2 (0.44) | HDAC6ALDH1A1LMNA | |
| SCHEMBL6936315 | 0.67 | TSHR (0.41) | TDP1ALDH1A1 | |
| SCHEMBL14861373 | 0.67 | TDP1 (0.48) | HDAC6TDP1OPRM1OPRD1ALDH1A1 | |
| SCHEMBL27478897 | 0.66 | TSHR (0.34) | TDP1ALDH1A1 | |
| SCHEMBL2226376 | 0.66 | SMN1; SMN2 (0.51) | TDP1ALDH1A1LMNAREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |