SCHEMBL1076061

SCHEMBL1076061

Nc1ccc(N(c2ccccc2)c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.42
▸ ALDH1A1 P00352 4/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ CYP3A4 P08684 2/20 0.42
▸ TDP1 Q9NUW8 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ HSD17B10 Q99714 3/20 0.34
▸ DYRK1A Q13627 2/20 0.33
▸ CHEK1 O14757 1/20 0.33
▸ NEK2 P51955 1/20 0.33
▸ LIMK1 P53667 1/20 0.33
▸ CLK4 Q9HAZ1 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ KMT2A Q03164 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ CRHBP P24387 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1827494 0.95 ALDH1A1 (0.38) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL18423115 0.95 ALDH1A1 (0.42) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL4885086 0.88 KDM4E (0.36) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL28957579 0.87 ALDH1A1 (0.41) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL27958625 0.83 ALDH1A1 (0.37) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL27862688 0.82 DYRK1A (0.38) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL18334397 0.81 ALDH1A1 (0.39) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL30526275 0.81 ALDH1A1 (0.39) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL17739951 0.80 L3MBTL1 (0.34) MAPTALDH1A1L3MBTL1CYP3A4TDP1
SCHEMBL4894233 0.80 CHEK1 (0.39) MAPTALDH1A1L3MBTL1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8071227-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2011-12-06 — — US disclosed
EP-1926795-B1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(1) LG CHEMICAL LTD (KR) 2011-01-19 — — EP disclosed
US-7842404-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2010-11-30 — — US disclosed
US-7838129-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2010-11-23 — — US disclosed
EP-1794258-B1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(4) LG CHEMICAL LTD (KR) 2010-09-01 — — EP disclosed
US-20100065828-A1 COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG CHEM, LTD. (KR) 2010-03-18 — — US disclosed
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-08-13 — — US disclosed
CN-101326654-A Color tunable light-emitting devices and method of making the same GEN ELECTRIC (US) 2008-12-17 — — CN disclosed
EP-1926795-A4 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(1) LG CHEMICAL LTD (KR) 2008-11-12 — — EP disclosed
EP-1794258-A4 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(4) LG CHEMICAL LTD (KR) 2008-11-05 — — EP disclosed
WO-2008066358-A1 NEW COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG CHEM, LTD. (KR) 2008-06-05 — — WO disclosed
EP-1926795-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(1) LG Chemical Co. Ltd (KR) 2008-06-04 — — EP disclosed
US-20070247059-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2007-10-25 — — US disclosed
EP-1794258-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(4) LG Chem, Ltd. (KR) 2007-06-13 — — EP disclosed
WO-2006080643-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(4) LG CHEM. LTD. (KR) 2006-08-03 — — WO disclosed
WO-2006080640-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(1) LG CHEM. LTD. (KR) 2006-08-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090200542-A1 Compounds and Organic Light Emitting Device Using the Same CYBA, LOXL1, OGDH MAPT 513/4885ALDH1A1 5/4885L3MBTL1 408/4885
US-20100065828-A1 COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME VDAC1, PER2, PPOX MAPT 1039/4885ALDH1A1 69/4885L3MBTL1 484/4885
US-20070247059-A1 Compound and Organic Light Emitting Device Using the Same PPOX, CRY1, CRY2 MAPT 100/4885ALDH1A1 318/4885L3MBTL1 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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