Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779891 | 0.84 | KISS1R (0.46) | CTSSCTSLCTSBCTSKTDP1 | |
| SCHEMBL10780784 | 0.80 | TAS1R3 (0.69) | CTSSCTSLCTSKGAATAS1R3 | |
| SCHEMBL7108670 | 0.77 | GRN (0.54) | KDM4EPOLB | |
| SCHEMBL21265876 | 0.75 | ALDH1A1 (0.49) | CTSSCTSLCTSBCTSKGAA | |
| SCHEMBL9807063 | 0.74 | CTSK (0.70) | CTSSCTSLCTSBCTSK | |
| SCHEMBL27504171 | 0.74 | KDM4E (0.47) | KDM4EPOLB | |
| SCHEMBL6756063 | 0.72 | CAPN9 (0.43) | CTSSCTSLCTSBCTSKGAA | |
| SCHEMBL13222147 | 0.72 | KDM4E (0.54) | GAAKDM4EPOLB | |
| SCHEMBL16628812 | 0.71 | CAPN9 (0.42) | CTSSCTSLCTSBCTSKGAA | |
| SCHEMBL16628790 | 0.71 | CAPN9 (0.42) | CTSSCTSLCTSBCTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099056-B1 | N-ACYL DERIVATIVES OF DIPEPTIDES, THEIR MANUFACTURE AND USE IN TREATING DISEASES, AND MEANS THEREFOR | BASF Aktiengesellschaft (DE) | 1987-09-30 | — | — | EP | disclosed |
| US-4610818-A | N-acyl derivatives of dipeptides, their preparation and their use in the therapy of disorders, and agents for this purpose | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0099056-A2 | N-acyl derivatives of dipeptides, their manufacture and use in treating diseases, and means therefor | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | disclosed |