SCHEMBL10794898

SCHEMBL10794898

CC(C)=CCc1[c]cccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
DHODH Q02127 3/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP3A4 P08684 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
PKM P14618 1/20 0.38
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
RPS6KA3 P51812 1/20 0.38
GLO1 Q04760 1/20 0.38
GPR35 Q9HC97 1/20 0.38
VKORC1 Q9BQB6 1/20 0.35
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3410244 0.85 MAPT (0.47) MEN1KMT2AMAPTCYP3A4ALDH1A1
SCHEMBL4623305 0.83 TRPA1 (0.43)
SCHEMBL6138617 0.82
SCHEMBL1702559 0.82
SCHEMBL526546 0.77
SCHEMBL7822554 0.74
SCHEMBL482794 0.73 MAOB (0.30) MAOB
SCHEMBL482877 0.73 MAOB (0.30) MAOB
SCHEMBL9199675 0.73 MAOB (0.30) MAOB
SCHEMBL20778 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024403-A1 Compositions and Methods for Managing Weight UNIGEN, INC. (US) 2024-01-25 US claimed
CN-113476499-A Compositions and methods for weight management 尤妮金公司 2021-10-08 CN claimed
CN-107281490-B Compositions and methods for weight management 尤妮金公司 2021-08-20 CN claimed
US-20180099019-A1 Compositions and Methods for Managing Weight UNIGEN, INC. (US) 2018-04-12 US claimed
US-20140004215-A1 COMPOSITIONS AND METHODS FOR MANAGING WEIGHT UNIGEN, INC. (KR) 2014-01-02 US claimed
WO-2013181296-A2 COMPOSITIONS AND METHODS FOR MANAGING WEIGHT UNIGEN, INC. (US) 2013-12-05 WO claimed
US-12042523-B2 Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof UNIGEN, INC. (US) 2024-07-23 US disclosed
US-20240024403-A1 Compositions and Methods for Managing Weight UNIGEN, INC. (US) 2024-01-25 US disclosed
US-20240024403-A1 Compositions and Methods for Managing Weight UNIGEN, INC. (US) 2024-01-25 US disclosed
CN-117224593-A Compositions and methods for managing or improving bone disorders, cartilage disorders, or both 尤尼根公司 2023-12-15 CN disclosed
CN-116785342-A Compositions and methods for managing or improving bone disorders, cartilage disorders, or both 尤尼根公司 2023-09-22 CN disclosed
US-20230201295-A1 Compositions and Methods for Managing or Improving Bone Disorders, Joint Disorders, Cartilage Disorders, or a Combination Thereof UNIGEN, INC. (US) 2023-06-29 US disclosed
US-20230190852-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH UNIGEN, INC. (US) 2023-06-22 US disclosed
WO-2013181296-A2 COMPOSITIONS AND METHODS FOR MANAGING WEIGHT UNIGEN, INC. (US) 2013-12-05 WO disclosed
EP-0151702-B1 ALPHA-HYDROXYKETONE ACETALS SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1987-11-25 EP disclosed
EP-0048136-B1 PROCESS FOR PREPARING ALPHA-AROMATIC GROUP SUBSTITUTED ALKANOIC ACIDS OR ESTERS THEREOF SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1986-06-11 EP disclosed
US-4539420-A Optically active 1-aromatic-group-substituted-1-alkanones and methods for their manufacture SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1985-09-03 US disclosed
EP-0151702-A2 Alpha-hydroxyketone acetals SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1985-08-21 EP disclosed
EP-0067698-A2 Optically active 1-aromatic-group-substituted-1-alkanones and methods for their manufacture SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1982-12-22 EP disclosed
EP-0048136-A2 Process for preparing alpha-aromatic group substituted alkanoic acids or esters thereof SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1982-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12042523-B2 Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof MATR3, ACACA, COL2A1 MEN1 2574/4885KMT2A 2507/4885DHODH 3651/4885
US-20240024403-A1 Compositions and Methods for Managing Weight LIPE, PNLIP, LIPC MEN1 3871/4885KMT2A 2720/4885DHODH 2123/4885
US-20180099019-A1 Compositions and Methods for Managing Weight LIPE, PNLIP, LIPC MEN1 3871/4885KMT2A 2720/4885DHODH 2123/4885
US-20140004215-A1 COMPOSITIONS AND METHODS FOR MANAGING WEIGHT LIPE, PNLIP, LIPC MEN1 3871/4885KMT2A 2720/4885DHODH 2123/4885
US-20230201295-A1 Compositions and Methods for Managing or Improving Bone Disorders, Joint Disorders, Cartilage Disorders, or a Combination Thereof MATR3, ACACA, COL2A1 MEN1 2574/4885KMT2A 2507/4885DHODH 3651/4885
US-20230190852-A1 COMPOSITIONS AND METHODS FOR JOINT HEALTH PTGES, PTGES3, PTGES2 MEN1 3730/4885KMT2A 3613/4885DHODH 2079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.