Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737387 | 0.82 | KDM4E (0.44) | MAOBMAOAMAPTNPC1ALDH1A1 | |
| SCHEMBL10816686 | 0.81 | L3MBTL1 (0.43) | EGLN1NPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL10815000 | 0.80 | RXRA (0.46) | EGLN1MAOBMAOANPC1ALDH1A1 | |
| SCHEMBL11021894 | 0.78 | ALKBH1 (0.41) | IDO1MAOBMAOAMAPTNPC1 | |
| SCHEMBL10811050 | 0.78 | EGLN1 (0.43) | EGLN1IDO1MAOBMAOANR4A2 | |
| SCHEMBL11018085 | 0.74 | RXRA (0.41) | EGLN1MAPTNPBWR1S1PR1NPC1 | |
| SCHEMBL10811918 | 0.74 | EGLN1 (0.39) | EGLN1NPBWR1NPC1HPGDRAB9A | |
| SCHEMBL27708411 | 0.71 | IDO1 (0.72) | IDO1MAOBNR4A2MAPTALDH1A1 | |
| SCHEMBL10815798 | 0.71 | HTT (0.39) | MAPTNPBWR1NPC1LMNACYP1A2 | |
| SCHEMBL10813995 | 0.70 | GABRA1 (0.37) | ALDH1A1LMNACYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087326-B1 | SUBSTITUTED PYRIMIDIN-2-ONES AND THE SALTS THEREOF | NYCOMED AS (NO) | 1987-05-13 | — | — | EP | disclosed |
| US-4539324-A | ANTICANCER AGENTS | NYEGAARD & CO. A/S (NO) | 1985-09-03 | — | — | US | disclosed |
| EP-0087326-A1 | Substituted pyrimidin-2-ones and the salts thereof | NYCOMED AS (NO) | 1983-08-31 | — | — | EP | disclosed |