SCHEMBL10824433

SCHEMBL10824433

ClCO[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TRPA1 O75762 1/20 0.30
MAPK1 P28482 1/20 0.30
GSK3B P49841 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701263 0.82 CYP1A2 (0.34) ALDH1A1
SCHEMBL23701154 0.81 KCNA3 (0.31)
SCHEMBL23701189 0.75
SCHEMBL675683 0.75 LTA4H (0.37) ALDH1A1
SCHEMBL23701036 0.73 TDP1 (0.37) ALDH1A1TRPA1
SCHEMBL863694 0.73 TSHR (0.50) ALDH1A1MAPK1HIF1A
SCHEMBL3481818 0.71 LMNA (0.39) ALDH1A1
SCHEMBL28833848 0.71 ALDH1A1 (0.37) ALDH1A1
SCHEMBL28797993 0.71 ALDH1A1 (0.46) ALDH1A1
SCHEMBL29221544 0.71 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61072791-A None JP disclosed
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
JP-S6172791-A PRODUCTION OF DIALKOXYDIPHENYLSILANE YUKI GOSEI YAKUHIN KOGYO KK 1986-04-14 JP disclosed