SCHEMBL108394

SCHEMBL108394

Oc1cccc2c1NCC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.43
BCL2L1 Q07817 1/20 0.42
BAD Q92934 1/20 0.42
SRC P12931 1/20 0.40
PNMT P11086 3/20 0.40
DRD2 P14416 4/20 0.39
DRD4 P21917 1/20 0.39
PDPK1 O15530 1/20 0.39
PARP10 Q53GL7 1/20 0.39
PARP11 Q9NR21 1/20 0.39
HTR2C P28335 1/20 0.39
ADCY6 O43306 1/20 0.37
ADCY3 O60266 1/20 0.37
ADCY9 O60503 1/20 0.37
ADCY5 O95622 1/20 0.37
ADCY8 P40145 1/20 0.37
ADCY7 P51828 1/20 0.37
ADCY2 Q08462 1/20 0.37
ADCY1 Q08828 1/20 0.37
ADCY4 Q8NFM4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30281891 0.88 SRC (0.53) PARP1BCL2L1BADSRCPNMT
SCHEMBL327043 0.88 SRC (0.53) PARP1BCL2L1BADSRCPNMT
Bromide SCHEMBL11832548 0.86 SRC (0.51) PARP1BCL2L1BADSRCPNMT
Hydrochloric Acid SCHEMBL8017722 0.86 SRC (0.51) PARP1BCL2L1BADSRCPNMT
SCHEMBL16860666 0.77 PNMT (0.55) PARP1BCL2L1BADSRCPNMT
SCHEMBL13977384 0.74 PARP1 (0.39) PARP1SRCPNMTDRD2DRD4
SCHEMBL1870062 0.74 PARP10 (0.43) PARP1SRCPNMTPDPK1PARP10
SCHEMBL5536927 0.74 PARP1 (0.39) PARP1SRCPNMTDRD2DRD4
SCHEMBL22926224 0.74 PARP1 (0.39) PARP1SRCPNMTDRD2DRD4
SCHEMBL515124 0.74 HTR5A (0.42) PARP1SRCPNMTDRD2PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US claimed
WO-2025061319-A2 IMPROVING THE WASHING FASTNESS OF LEVEL 2 COLORATIONS BY MEANS OF A SEALING PROCESS USING SILANES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
EP-4496558-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED ALKALISING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496555-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE P-PHENYLENEDIAMINE TYPE, ISATIN AND AT LEAST ONE OXIDISING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496559-A1 AGENT FOR OXIDATIVE DYEING OF KERATIN FIBRES, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496556-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, AT LEAST ONE OXIDATION DYE PRECURSOR OF THE COUPLER TYPE AND ISATIN Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496557-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED COMPLEXING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
US-20250025395-A1 Means for Oxidatively Dyeing Keratin Fibers HENKEL AG & CO. KGAA (DE) 2025-01-23 US claimed
US-20250025399-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE AND ISATIN HENKEL AG & CO. KGAA (DE) 2025-01-23 US claimed
US-20250017837-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2025-01-16 US claimed
US-9132073-B2 Oxidation dye precursors HENKEL AG & CO. KGAA (DE) 2015-09-15 US claimed
EP-2816992-A2 NOVEL OXIDATION DYE PRECURSORS Henkel AG & Co. KGaA (DE) 2014-12-31 EP claimed
US-20140359951-A1 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2014-12-11 US claimed
US-20140359950-A1 DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE AMANO ENZYME INC. (JP) 2014-12-11 US claimed
US-20140245541-A1 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2014-09-04 US claimed
US-8821592-B1 Oxidation dye precursors HENKEL AG & CO. KGAA (DE) 2014-09-02 US claimed
EP-2734179-A2 NOVEL OXIDATION DYE PRECURSORS Henkel AG & Co. KGaA (DE) 2014-05-28 EP claimed
WO-2013124363-A2 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2013-08-29 WO claimed
WO-2013013897-A2 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2013-01-31 WO claimed
WO-2013013861-A2 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2013-01-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017837-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS KRT18, OAT, SQOR PARP1 3081/4885BCL2L1 1913/4885BAD 3868/4885
US-20250025399-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE AND ISATIN OAT, KRT18, ARG2 PARP1 1582/4885BCL2L1 3196/4885BAD 3654/4885
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer KRT18, ARSA, MKI67 PARP1 376/4885BCL2L1 2902/4885BAD 4574/4885
US-20140245541-A1 NOVEL OXIDATION DYE PRECURSORS KRT18, SQOR, NDUFA5 PARP1 1656/4885BCL2L1 2409/4885BAD 3847/4885
US-20250025395-A1 Means for Oxidatively Dyeing Keratin Fibers KRT18, SQOR, ADH4 PARP1 2072/4885BCL2L1 1840/4885BAD 4183/4885
US-20140359951-A1 NOVEL OXIDATION DYE PRECURSORS KRT18, COXFA4L2, CYB5R3 PARP1 3288/4885BCL2L1 2374/4885BAD 4511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.