Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10842650 | 0.90 | NPSR1 (0.53) | THRBRECQLNPSR1TDP1POLB | |
| SCHEMBL10842466 | 0.89 | MEN1 (0.47) | THRBRECQLNPSR1TDP1MAPT | |
| SCHEMBL10842811 | 0.89 | NPBWR1 (0.42) | THRBRECQLNPSR1TDP1POLB | |
| SCHEMBL10841737 | 0.87 | THRB (0.61) | THRBRECQLNPSR1TDP1POLB | |
| SCHEMBL10842636 | 0.84 | POLB (0.51) | THRBRECQLNPSR1TDP1POLB | |
| SCHEMBL10842419 | 0.78 | KDM4E (0.36) | MAPTNPC1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL11849955 | 0.70 | L3MBTL1 (0.50) | THRBRECQLNPSR1TDP1POLB | |
| SCHEMBL17576255 | 0.66 | MAPT (0.63) | NPSR1TDP1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL11819978 | 0.65 | MAPT (0.41) | THRBRECQLNPSR1TDP1POLB | |
| SCHEMBL11367151 | 0.65 | MAPT (0.47) | TDP1POLBMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |