Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841715 | 0.89 | THRB (0.45) | NPBWR1TDP1NPSR1THRBRECQL | |
| SCHEMBL10842650 | 0.86 | NPSR1 (0.53) | TDP1NPSR1THRBRECQLHTT | |
| SCHEMBL10842466 | 0.84 | MEN1 (0.47) | NPBWR1TDP1NPSR1THRBRECQL | |
| SCHEMBL10841737 | 0.83 | THRB (0.61) | TDP1NPSR1THRBRECQLHPGD | |
| SCHEMBL10842636 | 0.80 | POLB (0.51) | TDP1NPSR1THRBRECQLHTT | |
| SCHEMBL10842100 | 0.80 | NPC1 (0.37) | TDP1NPSR1RECQLHTTHPGD | |
| SCHEMBL10842419 | 0.67 | KDM4E (0.36) | HTTHPGDMAPTALDH1A1LMNA | |
| SCHEMBL2660487 | 0.67 | NPBWR1 (0.54) | NPBWR1TDP1NPSR1RECQLHTT | |
| SCHEMBL11849955 | 0.67 | L3MBTL1 (0.50) | TDP1NPSR1THRBRECQLHPGD | |
| SCHEMBL13347519 | 0.66 | CASR (0.67) | NPBWR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |