Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643930 | 0.80 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1898445 | 0.79 | TSHR (0.39) | ALDH1A1TSHR | |
| SCHEMBL7192163 | 0.76 | TSHR (0.38) | ALDH1A1TSHRTHRB | |
| SCHEMBL2185442 | 0.76 | TSHR (0.37) | ALDH1A1TSHR | |
| SCHEMBL30335101 | 0.74 | — | — | |
| SCHEMBL261665 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL28411732 | 0.72 | — | — | |
| SCHEMBL305992 | 0.72 | — | — | |
| SCHEMBL5549372 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHRTHRB | |
| SCHEMBL28763054 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153705-B2 | Silyl esters, their use in binder systems and paint compositions and a process for production thereof | SIGMAKALON B.V. (NL) | 2012-04-10 | — | — | US | disclosed |
| US-8148446-B2 | Silyl esters, their use in binder systems and paint compositions and a process of production thereof | SIGMAKALON B.V. (NL) | 2012-04-03 | — | — | US | disclosed |
| US-20100249298-A1 | Silyl esters, their use in binder systems and paint compositions and a process of production thereof | GILLARD MICHEL | 2010-09-30 | — | — | US | disclosed |
| US-20070161722-A1 | Silyl Esters, Their Use in Binder Systems and Paint Compositions and a Process for Production Thereof | SIGMA COATINGS B.V. (NL) | 2007-07-12 | — | — | US | disclosed |
| EP-1620514-A2 | SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF | SigmaKalon B.V. (NL) | 2006-02-01 | — | — | EP | disclosed |
| US-20040236130-A1 | Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings | SIGMA COATINGS B.V. (NL) | 2004-11-25 | — | — | US | disclosed |
| WO-2004099326-A2 | SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF | SIGMAKALON B.V. (NL) | 2004-11-18 | — | — | WO | disclosed |
| EP-1475415-A1 | Silyl esters, their use in binder systems and paint compositions and a process of production thereof | SigmaKalon Services B.V. (NL) | 2004-11-10 | — | — | EP | disclosed |
| EP-1389214-A1 | PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS | SIGMA COATINGS B.V. (NL) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094838-A1 | PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS | SIGMA COATINGS B.V. (NL) | 2002-11-28 | — | — | WO | disclosed |
| EP-1260513-A1 | Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings | SIGMA COATINGS B.V. (NL) | 2002-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236130-A1 | Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings | ACMSD, OR10J3, CFD | ALDH1A1 223/4885TSHR 3555/4885THRB 2910/4885 |
| US-20100249298-A1 | Silyl esters, their use in binder systems and paint compositions and a process of production thereof | LCT, PCMT1, TST | ALDH1A1 2426/4885TSHR 4814/4885THRB 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.