Itaconate

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Itaconate SCHEMBL109061	0.89	ALDH1A1 (0.36)	ALDH1A1MAPTMAPK1USP2LMNA
	Malonic Acid SCHEMBL105770	0.85	CA4 (0.46)	MAPTMAPK1LMNAHDAC3HDAC4
	Malonic Acid SCHEMBL106051	0.81	RECQL (0.39)	ALDH1A1MAPTMAPK1HDAC3HDAC4
	Itaconate SCHEMBL104175	0.79	HDAC4 (0.33)	ALDH1A1MAPTMAPK1USP2LMNA
	Itaconate SCHEMBL10874716	0.79	HDAC3 (0.33)	ALDH1A1MAPTMAPK1USP2LMNA
	Oxalic Acid SCHEMBL105013	0.78	CA4 (0.44)	ALDH1A1MAPTLMNAPOLBKDM4E
	Succinic Acid SCHEMBL105103	0.77	HDAC3 (0.48)	ALDH1A1MAPTMAPK1LMNAHDAC3
	Oxalic Acid SCHEMBL107011	0.76	CA2 (0.42)	ALDH1A1MAPK1LMNACA4CES1
	Bicarbonate SCHEMBL105290	0.76	CA2 (0.46)	ALDH1A1MAPTLMNAPOLBNPSR1
	Bicarbonate SCHEMBL105292	0.76	CA2 (0.46)	ALDH1A1MAPTLMNAPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.