Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.33 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL8501991 | 1.00 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylic Acid SCHEMBL527602 | 1.00 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylic Acid SCHEMBL11419964 | 0.94 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylic Acid SCHEMBL28547955 | 0.94 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylic Acid SCHEMBL1100262 | 0.94 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylic Acid SCHEMBL15464233 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylic Acid SCHEMBL29031442 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylic Acid SCHEMBL8418695 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylamide SCHEMBL27880336 | 0.88 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4MEN1LDHA | |
| Acrylic Acid SCHEMBL673879 | 0.87 | TSHR (0.53) | ALDH1A1TSHRFGFR4MEN1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547299-A | Drilling fluid containing a copolymer filtration control agent | MILCHEM INCORPORATED (US) | 1985-10-15 | — | — | US | disclosed |
| US-4309329-A | FILTRATION CONTROL AGENTS | MILCHEM INCORPORATED (US) | 1982-01-05 | — | — | US | disclosed |
| US-4293427-A | (METH)ACRYLAMIDE-(METH)ACRYLAMIDOSULFONIC ACID COPOLYMER OPTIONALLY CROSSLINKED | MILCHEM INCORPORATED (US) | 1981-10-06 | — | — | US | disclosed |
| US-4288582-A | ALKALI ACRYLATE, HYDROXYALKYL ACRYLATE, ACRYLAMIDE TERPOLYMER | MILCHEM INCORPORATED (US) | 1981-09-08 | — | — | US | disclosed |
| US-4268400-A | TERPOLYMER OF ALKALI ACRYLATE, HYDROXYALKYL ACRYLATE AND ACRYLAMIDE | MILCHEM INCORPORATED (US) | 1981-05-19 | — | — | US | disclosed |