Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 7/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459856 | 0.97 | FABP3 (0.50) | FABP3EPHX2FAAHTERTMAPT | |
| SCHEMBL2123674 | 0.87 | CA2 (0.56) | EPHX2MAPTBLMPPARDRECQL | |
| SCHEMBL25301056 | 0.87 | CA2 (0.56) | EPHX2MAPTBLMPPARDRECQL | |
| SCHEMBL3018922 | 0.87 | CA2 (0.56) | EPHX2MAPTBLMPPARDRECQL | |
| SCHEMBL8076961 | 0.84 | FAAH (0.50) | FABP3EPHX2FAAHMAPTBLM | |
| SCHEMBL1534918 | 0.81 | FAAH (0.51) | FABP3EPHX2FAAHTERTMAPT | |
| SCHEMBL2231242 | 0.80 | EPHX2 (0.44) | FABP3EPHX2FAAH | |
| Sulfuric Acid SCHEMBL325122 | 0.80 | CA2 (0.67) | FABP3EPHX2FAAHMAPTBLM | |
| Potassium Ion SCHEMBL28636809 | 0.79 | CA2 (0.70) | FABP3FAAHTERTMAPTBLM | |
| Sulfuric Acid SCHEMBL2231589 | 0.79 | CA2 (0.70) | FABP3EPHX2FAAHMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612161-B | Improved composition and process for reverse froth flotation of phosphate ores | 埃科莱布美国股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-113631632-A | Dihydroxylactam-based polymers, compositions thereof and uses thereof | ISP投资有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-112437807-A | Coarse-particle solid nonionic synthetic associative thickener for paint formulations and method for producing the same | 赫尔克里士有限公司 | 2021-03-02 | — | — | CN | disclosed |
| US-20200338571-A1 | COMPOSITIONS AND METHODS FOR REVERSE FROTH FLOTATION OF PHOSPHATE ORES | ECOLAB USA INC. | 2020-10-29 | — | — | US | disclosed |
| US-10737281-B2 | Compositions and methods for reverse froth flotation of phosphate ores | ECOLAB USA INC. (US) | 2020-08-11 | — | — | US | disclosed |
| CN-110612161-A | Improved composition and process for reverse froth flotation of phosphate ores | 埃科莱布美国股份有限公司 | 2019-12-24 | — | — | CN | disclosed |
| US-20180345297-A1 | COMPOSITIONS AND METHODS FOR REVERSE FROTH FLOTATION OF PHOSPHATE ORES | ECOLAB USA INC. | 2018-12-06 | — | — | US | disclosed |
| EP-3334813-A1 | SULFATE-FREE LIQUID LAUNDRY DETERGENT | Henkel IP & Holding GmbH (DE) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017030996-A1 | SULFATE-FREE LIQUID LAUNDRY DETERGENT | THE SUN PRODUCTS CORPORATION (US) | 2017-02-23 | — | — | WO | disclosed |
| US-20170044471-A1 | Sulfate-Free Liquid Laundry Detergent | THE SUN PRODUCTS CORPORATION (US) | 2017-02-16 | — | — | US | disclosed |
| EP-2207757-A1 | INCORPORATION OF A RESIN DISPERSION TO IMPROVE THE MOISTURE RESISTANCE OF GYPSUM PRODUCTS | Eastman Chemical Company (US) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009058292-A1 | INCORPORATION OF A RESIN DISPERSION TO IMPROVE THE MOISTURE RESISTANCE OF GYPSUM PRODUCTS | EASTMAN CHEMICAL COMPANY (US) | 2009-05-07 | — | — | WO | disclosed |
| CN-101426878-A | Resin dispersions with low surfactant concentrations | EASTMAN CHEM CO (US) | 2009-05-06 | — | — | CN | disclosed |
| US-20090110946-A1 | INCORPORATION OF A RESIN DISPERSION TO IMPROVE THE MOISTURE RESISTANCE OF GYPSUM PRODUCTS | EASTMAN CHEMICAL COMPANY (US) | 2009-04-30 | — | — | US | disclosed |
| EP-2013306-A2 | TACKIFIER DISPERSIONS WITH IMPROVED HUMID AGE PERFORMANCE | Eastman Chemical Company (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-2010621-A1 | RESIN DISPERSIONS WITH LOW SURFACTANT CONCENTRATIONS | Eastman Chemical Company (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007124049-A2 | TACKIFIER DISPERSIONS WITH IMPROVED HUMID AGE PERFORMANCE | EASTMAN CHEMICAL COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007124052-A1 | RESIN DISPERSIONS WITH LOW SURFACTANT CONCENTRATIONS | EASTMAN CHEMICAL COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |
| US-20070254985-A1 | Resin dispersions with low surfactant concentrations | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| US-20070249759-A1 | Tackifier dispersions with improved humid age performance | EASTMAN CHEMICAL COMPANY | 2007-10-25 | — | — | US | disclosed |