SCHEMBL1094834

SCHEMBL1094834

CO[C@H](Cc1cccc(N)c1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SRR Q9GZT4 3/20 0.53
FFAR1 O14842 1/20 0.47
PPARG P37231 10/20 0.47
PPARA Q07869 10/20 0.47
PPARD Q03181 4/20 0.47
SLC7A5 Q01650 2/20 0.47
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
PLA2G10 O15496 1/20 0.44
PLA2G2A P14555 1/20 0.44
PLA2G5 P39877 1/20 0.44
PSAT1 Q9Y617 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL757308 1.00 SRR (0.53) SRRFFAR1PPARGPPARAPPARD
SCHEMBL1094835 1.00 SRR (0.53) SRRFFAR1PPARGPPARAPPARD
SCHEMBL15679980 1.00 SRR (0.53) SRRFFAR1PPARGPPARAPPARD
SCHEMBL756254 0.85 PPARG (0.57) PPARGPPARAPPARD
SCHEMBL28748038 0.85 SRR (0.47) SRRPPARGPPARASLC7A5
SCHEMBL1105056 0.84 MAOB (0.46) SRRSLC7A5MAOAMAOB
SCHEMBL5383259 0.83 SRR (0.50) SRRFFAR1PPARGPPARAPPARD
SCHEMBL31321016 0.83 PPARG (0.56) SRRFFAR1PPARGPPARAPPARD
SCHEMBL22264856 0.83 PPARG (0.56) SRRFFAR1PPARGPPARAPPARD
SCHEMBL22264858 0.83 PPARG (0.56) SRRFFAR1PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12291494-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2025-05-06 US disclosed
US-20240279157-A1 METHODS OF TREATING FIBROSIS NOGRA PHARMA LIMITED (IE) 2024-08-22 US disclosed
US-11753365-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2023-09-12 US disclosed
US-20220033346-A1 METHODS OF TREATING FIBROSIS NOGRA PHARMA LIMITED (IE) 2022-02-03 US disclosed
US-11046641-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2021-06-29 US disclosed
US-20210113505-A1 METHODS OF TREATING HAIR RELATED CONDITIONS NOGRA PHARMA LTD (IE) 2021-04-22 US disclosed
EP-3628317-A1 METHODS OF TREATING FIBROSIS Nogra Pharma Limited (IE) 2020-04-01 EP disclosed
EP-2811993-B1 METHODS OF TREATING FIBROSIS NOGRA PHARMA LTD (IE) 2019-10-09 EP disclosed
US-10016381-B2 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field NOGRA PHARMA LIMITED (IE) 2018-07-10 US disclosed
EP-2895160-B1 METHODS OF TREATING HAIR RELATED CONDITIONS NOGRA PHARMA LTD (IE) 2018-05-30 EP disclosed
EP-2355809-A1 METHODS FOR PREVENTING OR REDUCING COLON CARCINOGENESIS Giuliani International Limited (IE) 2011-08-17 EP disclosed
EP-2355810-A2 METHODS FOR PREVENTING OR REDUCING CARCINOGENESIS OR OXIDATIVE STRESS Giuliani International Limited (IE) 2011-08-17 EP disclosed
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants NOGRA PHARMA LIMITED (IE) 2011-06-23 US disclosed
WO-2010063472-A1 METHODS FOR PREVENTING OR REDUCING COLON CARCINOGENESIS GIULIANI INTERNATIONAL LIMITED (IE) 2010-06-10 WO disclosed
WO-2010063470-A2 METHODS FOR PREVENTING OR REDUCING CARCINOGENESIS OR OXIDATIVE STRESS GIULIANI INTERNATIONAL LIMITED (IE) 2010-06-10 WO disclosed
EP-2131829-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS Giuliani International Limited (IE) 2009-12-16 EP disclosed
US-20090048343-A1 Compounds and Their Salts Specific to the PPAR Receptors and the EGF Receptors and Their Use in the Medical Field NOGRA PHARMA LIMITED (IE) 2009-02-19 US disclosed
WO-2008104557-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS GIULIANI INTERNATIONAL LIMITED (IE) 2008-09-04 WO disclosed
EP-1910270-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD Giuliani International Limited (IE) 2008-04-16 EP disclosed
WO-2007010516-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD GIULIANI INTERNATIONAL LIMITED (IE) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10016381-B2 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field EGFR, ERBB3, FGFR3 SRR 1855/4885FFAR1 55/4885PPARG 4/4885
US-11753365-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 SRR 3600/4885FFAR1 2768/4885PPARG 669/4885
US-20210113505-A1 METHODS OF TREATING HAIR RELATED CONDITIONS EBP, AADAT, ALDH7A1 SRR 1482/4885FFAR1 946/4885PPARG 69/4885
US-20240279157-A1 METHODS OF TREATING FIBROSIS MMP1, MMP8, FABP2 SRR 3600/4885FFAR1 2768/4885PPARG 669/4885
US-20090048343-A1 Compounds and Their Salts Specific to the PPAR Receptors and the EGF Receptors and Their Use in the Medical Field EGFR, ERBB3, FGFR3 SRR 1855/4885FFAR1 55/4885PPARG 4/4885
US-12291494-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 SRR 3600/4885FFAR1 2768/4885PPARG 669/4885
US-11046641-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 SRR 3600/4885FFAR1 2768/4885PPARG 669/4885
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants PPARG, FABP2, PPARD SRR 1693/4885FFAR1 87/4885PPARG 1/4885
US-20220033346-A1 METHODS OF TREATING FIBROSIS MMP1, MMP8, FABP2 SRR 3600/4885FFAR1 2768/4885PPARG 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.