SCHEMBL1102422

SCHEMBL1102422

CC(C)c1nc2ccccc2nc1-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
KDM4E B2RXH2 8/20 0.52
PKM P14618 1/20 0.52
L3MBTL1 Q9Y468 6/20 0.50
ALDH1A1 P00352 5/20 0.50
LMNA P02545 4/20 0.50
GAA P10253 3/20 0.50
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
AKT1 P31749 1/20 0.47
AKT2 P31751 1/20 0.47
PDE10A Q9Y233 2/20 0.47
HRH4 Q9H3N8 1/20 0.44
ATM Q13315 1/20 0.43
TLR9 Q9NR96 1/20 0.43
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
MAPK1 P28482 1/20 0.42
CASP1 P29466 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24702664 0.96 TDP1 (0.56) TDP1KDM4EPKML3MBTL1ALDH1A1
SCHEMBL3661077 0.88 TDP1 (0.55) TDP1KDM4EPKML3MBTL1ALDH1A1
SCHEMBL23776295 0.88 TDP1 (0.43) TDP1KDM4EPKML3MBTL1ALDH1A1
SCHEMBL8020858 0.87 MAPK14 (0.54) TDP1KDM4EPKMALDH1A1KMT2A
SCHEMBL714455 0.85 TDP1 (0.41) TDP1KDM4EPKML3MBTL1ALDH1A1
SCHEMBL8008310 0.85 MAPK14 (0.57) TDP1KDM4EL3MBTL1ALDH1A1LMNA
SCHEMBL6725538 0.85 TDP1 (0.45) TDP1KDM4EPKML3MBTL1ALDH1A1
SCHEMBL12721805 0.84 NPC1 (0.49) TDP1KDM4EL3MBTL1ALDH1A1LMNA
SCHEMBL23776022 0.83 SRC (0.42) TDP1KDM4EL3MBTL1ALDH1A1LMNA
SCHEMBL13787414 0.83 KDM4E (0.68) TDP1KDM4EPKML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 US disclosed
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
US-20220399506-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-15 US disclosed
US-20220393116-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed
US-20210328154-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed
US-20210253586-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-08-19 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-7888863-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2011-02-15 US disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100072888-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-25 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, FZD7 TDP1 3453/4885KDM4E 3940/4885PKM 1708/4885
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 TDP1 3901/4885KDM4E 4170/4885PKM 1130/4885
US-20100072888-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOC2, SCO2, C1S TDP1 3856/4885KDM4E 4319/4885PKM 3653/4885
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, TERT, VDAC2 TDP1 260/4885KDM4E 684/4885PKM 2037/4885
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A TDP1 3222/4885KDM4E 4138/4885PKM 3871/4885
US-20220393116-A1 ELECTROLUMINESCENT DEVICE L1CAM, MCOLN2, MCOLN1 TDP1 3468/4885KDM4E 1125/4885PKM 1479/4885
US-20220399506-A1 ELECTROLUMINESCENT DEVICE L1CAM, LDHA, LDHB TDP1 4357/4885KDM4E 1597/4885PKM 1838/4885
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 TDP1 2273/4885KDM4E 3298/4885PKM 708/4885
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 TDP1 4231/4885KDM4E 3367/4885PKM 1397/4885
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF OCIAD1, OCIAD2, OSTC TDP1 3544/4885KDM4E 3554/4885PKM 2624/4885
US-20210253586-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, RIF1 TDP1 290/4885KDM4E 3003/4885PKM 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.