SCHEMBL1103700

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14515992	0.95	PTGES (0.37)	DHODHASIC1KIF11RXRARXRB
	SCHEMBL13615706	0.93	PTGES (0.39)	DHODHASIC1KIF11RXRARXRB
	SCHEMBL12770708	0.92	PTGES (0.41)	DHODHKIF11RXRARXRBPTGES
	SCHEMBL10304794	0.92	PTGES (0.37)	KIF11PTGESALOX5CYP2D6HSD17B2
	SCHEMBL13706643	0.91	DHODH (0.33)	DHODHASIC1KIF11RXRARXRB
	SCHEMBL10304792	0.90	PTGES (0.38)	KIF11PTGESALOX5CYP2D6HSD17B2
	SCHEMBL13615686	0.89	TP53 (0.37)	KIF11PTGESALOX5CYP2D6MEN1
	SCHEMBL12928329	0.89	TP53 (0.37)	KIF11PTGESALOX5CYP2D6MEN1
	SCHEMBL13615646	0.89	TP53 (0.37)	KIF11PTGESALOX5CYP2D6MEN1
	SCHEMBL14100083	0.89	ALDH1A1 (0.38)	CYP2D6HSD17B2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.