SCHEMBL11043560

SCHEMBL11043560

CC(C)OC(=S)OC(C)C

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA9 Q16790 2/20 0.56
TSHR P16473 1/20 0.42
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28637724 0.86 CA12 (0.50) CA12CA1CA2CA9TSHR
SCHEMBL29233531 0.83
SCHEMBL10771408 0.74
SCHEMBL10196614 0.74
SCHEMBL10850846 0.74
SCHEMBL7236067 0.72
SCHEMBL2257027 0.72
SCHEMBL10158920 0.72
SCHEMBL9870252 0.72 CA12 (0.50) CA12CA1CA2CA9TSHR
SCHEMBL134436 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0042688-B1 WEED CONTROL USING 3-(4-ISOPROPYLPHENYL)-1,1-DIMETHYLUREA IN COMBINATION WITH S-2,3,3-TRICHLOROALLYL DIISOPROPYLTHIOCARBAMATE MAY & BAKER LIMITED (GB) 1984-01-18 EP claimed
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-11679120-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-06-20 US disclosed
US-9765022-B2 Disulfide compounds for delivery of pharmaceutical agents TUFTS UNIVERSITY (US) 2017-09-19 US disclosed
US-20170224839-A1 NANOPARTICLES FOR DRUG DELIVERY UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2017-08-10 US disclosed
US-20160082126-A1 NANOCOMPLEXES FOR DELIVERY OF SAPORIN UNIV TUFTS (US) 2016-03-24 US disclosed
US-20160009643-A1 DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS TRUSTEES OF TUFTS COLLEGE 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11771715-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB CA12 3727/4885CA1 4251/4885CA2 4784/4885
US-20160009643-A1 DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS P4HB, PDIA6, PDIA5 CA12 2187/4885CA1 2540/4885CA2 3160/4885
US-20170224839-A1 NANOPARTICLES FOR DRUG DELIVERY MSN, CD47, MTHFD1 CA12 123/4885CA1 254/4885CA2 597/4885
US-20160082126-A1 NANOCOMPLEXES FOR DELIVERY OF SAPORIN SARNP, SAP30BP, SCP2 CA12 2443/4885CA1 3034/4885CA2 3863/4885
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB CA12 3727/4885CA1 4251/4885CA2 4784/4885
US-11679120-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB CA12 3727/4885CA1 4251/4885CA2 4784/4885
US-11766449-B2 Circular RNA compositions and methods RTCB, RNGTT, HNRNPAB CA12 4043/4885CA1 4560/4885CA2 4833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.