Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.64 |
| ▸ | DPP4 | P27487 | 2/20 | 0.57 |
| ▸ | PNMT | P11086 | 3/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7895201 | 0.97 | TAAR1 (0.61) | TAAR1DPP4PNMTAKR1B1SMN1; SMN2 | |
| SCHEMBL932553 | 0.85 | PNMT (0.67) | TAAR1DPP4PNMTAKR1B1SMN1; SMN2 | |
| SCHEMBL30528615 | 0.85 | TAAR1 (0.54) | TAAR1DPP4PNMTAKR1B1SMN1; SMN2 | |
| SCHEMBL2833792 | 0.85 | TAAR1 (0.54) | TAAR1DPP4PNMTAKR1B1SMN1; SMN2 | |
| SCHEMBL113076 | 0.83 | TAAR1 (0.73) | TAAR1DPP4PNMTSMN1; SMN2MEN1 | |
| SCHEMBL1127909 | 0.83 | TAAR1 (0.52) | TAAR1DPP4PNMTAKR1B1SMN1; SMN2 | |
| SCHEMBL6822756 | 0.83 | TAAR1 (0.52) | TAAR1DPP4PNMTAKR1B1SMN1; SMN2 | |
| SCHEMBL19825564 | 0.83 | TAAR1 (0.52) | TAAR1DPP4PNMTAKR1B1SMN1; SMN2 | |
| SCHEMBL31737298 | 0.83 | TAAR1 (0.52) | TAAR1DPP4PNMTAKR1B1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11150443 | 0.81 | TAAR1 (0.70) | TAAR1DPP4PNMTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510429-A | Compound containing methyl isoxazole structure, and preparation method and application thereof | 中国农业大学 | 2024-02-06 | — | — | CN | claimed |
| CN-112625039-A | Pyrroloquinoline compound and synthesis method thereof | 湘潭大学 | 2021-04-09 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-9884839-B2 | Inhibitors of 17Beta-hydroxysteroid dehydrogenases type 1 and type 2 | ELEXOPHARM GMBH (DE) | 2018-02-06 | — | — | US | claimed |
| EP-3089969-A2 | INHIBITORS OF 17BETA-HYDROXYSTEROID DEHYDROGENASES TYPE 1 AND TYPE 2 | Elexopharm GmbH (DE) | 2016-11-09 | — | — | EP | claimed |
| US-20160318895-A1 | Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 | ELEXOPHARM GMBH (DE) | 2016-11-03 | — | — | US | claimed |
| CN-102388060-B | Actagardine derivatives | NOVACTA BIOSYSTEMS LTD | 2014-09-10 | — | — | CN | claimed |
| EP-2006271-A9 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2009-07-29 | — | — | EP | claimed |
| CN-101410366-A | Substituted bicyclic ring derivatives and uses thereof | ASAHI KASEI PHARMA CORP (JP) | 2009-04-15 | — | — | CN | claimed |
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-26 | — | — | US | claimed |
| US-7253171-B2 | Urea derivatives as integrin α4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2007-08-07 | — | — | US | claimed |
| US-20040142982-A1 | Urea derivatives as integrin alpha 4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2004-07-22 | — | — | US | claimed |
| EP-1383750-A2 | UREA DERIVATIVES AS INTEGRIN ALPHA 4 ANTAGONISTS | Almirall Prodesfarma, S.A. (ES) | 2004-01-28 | — | — | EP | claimed |
| US-6649799-B2 | Catalytic hydrogenation using a Raney catalyst in the form of hollow bodies; hexamethylenediamine from adiponitrile | DEGUSSA AG (DE) | 2003-11-18 | — | — | US | claimed |
| EP-1343749-A2 | METHOD FOR PRODUCING PRIMARY AND SECONDARY AMINES BY HYDROGENATING NITRILES AND IMINES | Degussa AG (DE) | 2003-09-17 | — | — | EP | claimed |
| US-20020173676-A1 | Method for producing primary and secondary amines by hydrogenation of nitriles and imines | DEGUSSA AG (DE) | 2002-11-21 | — | — | US | claimed |
| WO-2002057242-A2 | UREA DERIVATIVES AS INTEGRIN ALPHA 4 ANTAGONISTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2002-07-25 | — | — | WO | claimed |
| WO-2002051791-A2 | METHOD FOR PRODUCING PRIMARY AND SECONDARY AMINES BY HYDROGENATING NITRILES AND IMINES | DEGUSSA AG (DE) | 2002-07-04 | — | — | WO | claimed |
| EP-0363643-A1 | Pesticides based on partially different 2-aryl-substituted 1-10-phenanthrolines, and their preparation | BAYER AG (DE) | 1990-04-18 | — | — | EP | claimed |
| EP-0282893-A2 | Pesticides based on 1,10-phenanthrolines | BAYER AG (DE) | 1988-09-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | LTB4R2, LTC4S, LTB4R | TAAR1 1127/4885DPP4 4105/4885PNMT 3102/4885 |
| US-20160318895-A1 | Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 | HSD17B1, HSD17B2, HSD17B3 | TAAR1 3770/4885DPP4 1188/4885PNMT 3041/4885 |
| US-20040142982-A1 | Urea derivatives as integrin alpha 4 antagonists | ITGA4, ITGB4, ITGA1 | TAAR1 2288/4885DPP4 1678/4885PNMT 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.