SCHEMBL1104848

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1104845	0.94	ALDH1A1 (0.54)	ALDH1A1NLRP3MEN1KMT2AMAPT
	SCHEMBL1104831	0.91	NLRP3 (0.61)	ALDH1A1NLRP3SIRT2SIRT1ESR1
	SCHEMBL10979856	0.90	NLRP3 (0.60)	ALDH1A1NLRP3SIRT2SIRT1ESR1
	SCHEMBL1104839	0.89	ALDH1A1 (0.58)	ALDH1A1NLRP3MEN1KMT2AMAPT
	SCHEMBL13486686	0.88	SIRT2 (0.62)	ALDH1A1NLRP3SIRT2SIRT1ESR1
	SCHEMBL1104853	0.85	AOC3 (0.53)	ALDH1A1NLRP3MEN1KMT2AMAPT
	SCHEMBL1104858	0.85	MDM2 (0.59)	ALDH1A1NLRP3MAPTSIRT2SIRT1
	SCHEMBL20776081	0.83	MEN1 (0.54)	ALDH1A1MEN1KMT2AMAPTHSP90AA1
	SCHEMBL1104864	0.83	ALDH1A1 (0.54)	ALDH1A1NLRP3MEN1KMT2AMAPT
	SCHEMBL20776080	0.82	MEN1 (0.53)	ALDH1A1MEN1KMT2AMAPTHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.