Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104855 | 0.83 | RAB9A (0.59) | KDM4EALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL12210806 | 0.81 | ESRRA (0.63) | KDM4EALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL8427653 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL1704422 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1RAB9ANPC1TLR8 | |
| SCHEMBL30263662 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL23638274 | 0.80 | TLR8 (0.43) | KDM4EALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL1704421 | 0.80 | TLR8 (0.58) | KDM4EALDH1A1RAB9ANPC1TLR8 | |
| SCHEMBL960479 | 0.80 | ALDH1A1 (0.55) | KDM4EALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL521102 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL979518 | 0.80 | TLR8 (0.58) | KDM4EALDH1A1RAB9ANPC1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647311-B1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-20230295154-A1 | HETEROCYCLIC GLP-1 AGONISTS | SHOUTI INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230234968-A1 | METHYL-SUBSTITUTED BENZOBISOXAZOLE COMPOUND AND USE THEREOF | TONGHUA DONGBAO PHARMACEUTICAL CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230234937-A1 | INDENOAZANAPHTHALENES | MERCK PATENT GMBH (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20230234943-A1 | TREX1 INHIBITORS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-11696499-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-07-04 | — | — | US | disclosed |
| US-11678498-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-06-13 | — | — | US | disclosed |
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-06-01 | — | — | US | disclosed |
| US-20220407018-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2022-12-22 | — | — | US | disclosed |
| EP-3502107-B1 | 1-AMINODIBENZOFURAN-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO LTD (KR) | 2022-01-26 | — | — | EP | disclosed |
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-27 | — | — | US | disclosed |
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-27 | — | — | US | disclosed |
| US-20080292904-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS | SONY CORPORATION (JP) | 2008-11-27 | — | — | US | disclosed |
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-20 | — | — | US | disclosed |
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-20 | — | — | US | disclosed |
| US-20080258613-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20080258613-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20080233387-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE | SONY CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
| US-20080233387-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE | SONY CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
| WO-2007034251-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234943-A1 | TREX1 INHIBITORS AND USES THEREOF | FEN1, ERCC4, DCLRE1B | KDM4E 2430/4885ALDH1A1 1451/4885LMNA 387/4885 |
| US-20230295154-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | KDM4E 3398/4885ALDH1A1 840/4885LMNA 3670/4885 |
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | KDM4E 3442/4885ALDH1A1 1778/4885LMNA 3402/4885 |
| US-20220407018-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | PPOX, EPCAM, STOM | KDM4E 2892/4885ALDH1A1 1724/4885LMNA 3447/4885 |
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | KDM4E 3992/4885ALDH1A1 1368/4885LMNA 3213/4885 |
| US-20230234968-A1 | METHYL-SUBSTITUTED BENZOBISOXAZOLE COMPOUND AND USE THEREOF | CYP11B2, CYP11B1, TPMT | KDM4E 362/4885ALDH1A1 1062/4885LMNA 2923/4885 |
| US-20230234937-A1 | INDENOAZANAPHTHALENES | NQO1, CYP2D6, SQOR | KDM4E 1585/4885ALDH1A1 280/4885LMNA 4477/4885 |
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | KDM4E 3442/4885ALDH1A1 1778/4885LMNA 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.