Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105684 | 0.83 | PDE3B (0.39) | PDE3BPDE3ASIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL29291837 | 0.72 | MAOA (0.38) | PDE3BPDE3ASIRT3TDP1 | |
| SCHEMBL47849 | 0.71 | NOS3 (0.43) | SIGMAR1TDP1 | |
| SCHEMBL18996013 | 0.71 | — | — | |
| Iodide SCHEMBL28304051 | 0.70 | HRH4 (0.42) | SIGMAR1 | |
| SCHEMBL27484555 | 0.70 | HRH4 (0.42) | SIGMAR1 | |
| SCHEMBL30225967 | 0.68 | SIRT3 (0.43) | PDE3BPDE3ASIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL10354186 | 0.68 | PDE3B (0.41) | PDE3BPDE3ATDP1 | |
| SCHEMBL14452876 | 0.67 | SIGMAR1 (0.48) | PDE3BPDE3ASIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL29699898 | 0.67 | SIGMAR1 (0.48) | PDE3BPDE3ASIGMAR1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864015-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATEIVES | BAYER AG (DE) | 2023-05-10 | — | — | EP | disclosed |
| US-20180093958-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC PRODUCT | ZEON CORPORATION (JP) | 2018-04-05 | — | — | US | disclosed |
| US-9868710-B2 | Polymerizable compound, polymerizable composition, polymer, and optically anisotropic product | ZEON CORPORATION (JP) | 2018-01-16 | — | — | US | disclosed |
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | Rhe Trustees of The University of Pennsylvania | 2017-06-22 | — | — | US | disclosed |
| US-20160257659-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC PRODUCT | ZEON CORPORATION (JP) | 2016-09-08 | — | — | US | disclosed |
| US-9250249-B2 | Autophagy and phospholipidosis pathway assays | ENZO BIOCHEM, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-8846952-B2 | Detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | ENZO LIFE SCIENCES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8759526-B2 | Dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes—useful or detection or quantification of desirable target molecules | ENZO LIFE SCIENCES, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8674102-B2 | Fluorescent dyes | ENZO LIFE SCIENCES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8574881-B2 | Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-8389729-B2 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20130045480-A1 | Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-8357801-B2 | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits | ENZO LIFE SCIENCES, INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-8153802-B2 | Dyes linked to target molecules, oligonucleotides or polynucleotides comprising dye molecules, composite dyes and other compositions useful for detecting or quantifying desirable target molecules | ENZO LIFE SCIENCES, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20120040430-A1 | Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-20100228008-A1 | Dyes linked to target molecules, oligonucleotides or polynucleotides comprising dye molecules, composite dyes and other compositions useful for detecting or quantifying desirable target molecules | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100093004-A1 | Autophagy and phospholipidosis pathway assays | ENZO LIFE SCIENCES, INC. | 2010-04-15 | — | — | US | disclosed |
| US-20100041020-A1 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-20090226954-A1 | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits | ENZO LIFE SCIENCES, INC. | 2009-09-10 | — | — | US | disclosed |
| US-7569695-B2 | Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization | ENZO LIFE SCIENCES, INC. (US) | 2009-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257659-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC PRODUCT | CCNA1, PYM1, SCO2 | PDE3B 4545/4885PDE3A 4664/4885SIGMAR1 2208/4885 |
| US-20090226954-A1 | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits | SSBP1, IMMT, DNAJA3 | PDE3B 4778/4885PDE3A 4804/4885SIGMAR1 1375/4885 |
| US-20130045480-A1 | Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules | ANXA5, DCLRE1B, ANXA4 | PDE3B 4471/4885PDE3A 4445/4885SIGMAR1 1845/4885 |
| US-20170174678-A1 | NOVEL ANTIVIRAL COMPOUNDS AND METHODS USING SAME | ZC3HAV1, MAVS, ZC3HAV1L | PDE3B 1852/4885PDE3A 2148/4885SIGMAR1 671/4885 |
| US-20180093958-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC PRODUCT | CCNA2, CCNB2, CCNA1 | PDE3B 4524/4885PDE3A 4535/4885SIGMAR1 1928/4885 |
| US-20100228008-A1 | Dyes linked to target molecules, oligonucleotides or polynucleotides comprising dye molecules, composite dyes and other compositions useful for detecting or quantifying desirable target molecules | ANXA5, POLRMT, DCLRE1B | PDE3B 4525/4885PDE3A 4465/4885SIGMAR1 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.