Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24783320 | 0.76 | CRBN (0.54) | MAPTTSHRMEN1KMT2ADDB1 | |
| SCHEMBL11079063 | 0.75 | MAPT (0.45) | MAPTTSHRCASP1TP53CYP1A2 | |
| SCHEMBL11092005 | 0.70 | MAPT (0.40) | MAPTTSHRCASP1TP53CYP1A2 | |
| SCHEMBL11091982 | 0.68 | OPRK1 (0.41) | TRPM5MAPTOPRK1PDE4DGFER | |
| SCHEMBL11660617 | 0.68 | MEN1 (0.49) | TRPM5MAPTTSHRCASP1TP53 | |
| SCHEMBL26744897 | 0.66 | DDB1 (0.48) | MAPTTSHRCASP1MEN1KMT2A | |
| SCHEMBL4374687 | 0.66 | LMNA (0.39) | MAPTTSHRCASP1TP53CYP1A2 | |
| SCHEMBL5568413 | 0.65 | GSK3B (0.73) | TRPM5TSHRCASP1TP53CYP2C19 | |
| SCHEMBL6907817 | 0.64 | ALDH1A1 (0.46) | MAPTTSHRMEN1KMT2ADDB1 | |
| SCHEMBL9525760 | 0.63 | TRPM5 (0.42) | TRPM5TP53DDB1CRBNSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476133-A | CENTRAL NERVOUS SYSTEM DISORDERS | SHIONOGI & CO., LTD. (JP) | 1984-10-09 | — | — | US | disclosed |
| US-4374842-A | CENTRAL NERVOUS SYSTEM | SHIONOGI & CO., LTD. (JP) | 1983-02-22 | — | — | US | disclosed |