Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478228 | 0.87 | MAPT (0.52) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL14478209 | 0.87 | MAPT (0.52) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL10819607 | 0.87 | GPR35 (0.51) | GABRA1GABRB2POLBMAPK1ALDH1A1 | |
| SCHEMBL833871 | 0.84 | POLB (0.48) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL13604867 | 0.84 | GRM4 (0.51) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL11807538 | 0.81 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1ALOX15ALOX12 | |
| SCHEMBL3681751 | 0.81 | GPR35 (0.55) | MAPK1ALDH1A1HPGDGPR35MAPT | |
| SCHEMBL1025776 | 0.81 | POLB (0.56) | POLBMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL6766339 | 0.81 | FBP1 (0.45) | GABRA1GABRB2ALDH1A1TSHRMAPT | |
| SCHEMBL10510226 | 0.81 | MAPT (0.52) | POLBMAPK1ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535003-B | Process for nitration of para-alkylphenols | 福建振新化学有限公司 | 2021-12-03 | — | — | CN | disclosed |
| US-9034850-B2 | Gonadotropin releasing hormone receptor antagonist, preparation method thereof and pharmaceutical composition comprising the same | SK CHEMICALS CO., LTD. (KR) | 2015-05-19 | — | — | US | disclosed |
| US-8673904-B2 | Epoxide inhibitors of cysteine proteases | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-03-18 | — | — | US | disclosed |
| US-8673904-B2 | Epoxide inhibitors of cysteine proteases | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-03-18 | — | — | US | disclosed |
| US-20130137661-A1 | Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same | SK CHEMICALS CO. LTD. (KR) | 2013-05-30 | — | — | US | disclosed |
| US-8153440-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| WO-2011089257-A1 | METHOD FOR DETERMINING THE ACTIVITY OF TRANSGLUTAMINASE FACTOR XIIIA | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2011-07-28 | — | — | WO | disclosed |
| US-20110086431-A1 | Methods for Altering Surface Characteristics of Microspheres | LUMINEX CORPORATION (US) | 2011-04-14 | — | — | US | disclosed |
| US-7867774-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2011-01-11 | — | — | US | disclosed |
| US-7867774-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2011-01-11 | — | — | US | disclosed |
| US-20080176841-A1 | EPOXIDE INHIBITORS OF CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2008-07-24 | — | — | US | disclosed |
| US-20080176841-A1 | EPOXIDE INHIBITORS OF CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2008-07-24 | — | — | US | disclosed |
| US-7345040-B2 | Reverse-turn mimetics and compositions and methods relating thereto | MYRIAD GENETICS, INC. (US) | 2008-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137661-A1 | Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same | GNRHR, GHRHR, LHCGR | GABRA1 285/4885GABRB2 262/4885POLB 3291/4885 |
| US-20080176841-A1 | EPOXIDE INHIBITORS OF CYSTEINE PROTEASES | SERPINB1, EPHX1, EPX | GABRA1 4644/4885GABRB2 4542/4885POLB 2278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.