Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.37 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.37 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.37 |
| ▸ | CACNA2D3 | Q8IZS8 | 1/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092598 | 0.85 | MAPT (0.39) | CXCR2CDC25BCASP7MAPTALDH1A1 | |
| SCHEMBL11095030 | 0.84 | GSK3B (0.36) | CACNA1BCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL117727 | 0.84 | CACNB4 (0.40) | CACNA1BCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL10712822 | 0.81 | ALDH1A1 (0.40) | CACNA1BCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11093677 | 0.77 | CACNB4 (0.36) | CACNA1BCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL11368672 | 0.73 | DAO (0.40) | MAPTALDH1A1KMT2AGSK3BMEN1 | |
| SCHEMBL15966870 | 0.73 | AHR (0.62) | CACNA1BCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL10711888 | 0.71 | BRD4 (0.40) | PTGS2MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11094086 | 0.71 | HTR1A (0.34) | ALDH1A1CYP2C9CYP2C19KMT2AKDM4E | |
| SCHEMBL10713399 | 0.70 | PGR (0.36) | CACNA1BCACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |