Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092598 | 0.88 | MAPT (0.39) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL11097244 | 0.84 | CACNA1B (0.37) | GSK3BMEN1KMT2ALMNAMAPT | |
| SCHEMBL117727 | 0.76 | CACNB4 (0.40) | MAPTSMN1; SMN2CACNB4CACNA1ACACNA1G | |
| SCHEMBL11471168 | 0.73 | NR4A1 (0.41) | KMT2ALMNAMAPT | |
| SCHEMBL11368672 | 0.71 | DAO (0.40) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10713399 | 0.71 | PGR (0.36) | GSK3BMAPTCACNB4CACNA1ACACNA1G | |
| SCHEMBL10712822 | 0.70 | ALDH1A1 (0.40) | GSK3BKMT2AMAPTSMN1; SMN2CACNB4 | |
| SCHEMBL11094086 | 0.69 | HTR1A (0.34) | MEN1KMT2AALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1321330 | 0.68 | HTR2C (0.46) | MEN1KMT2AMAPTCACNA1BALDH1A1 | |
| SCHEMBL11093677 | 0.68 | CACNB4 (0.36) | MAPTSMN1; SMN2CACNB4CACNA1ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |