Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Phenolsulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.45 |
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 known ✓ | P03372 | 2/20 | 0.42 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenolsulfonic Acid SCHEMBL32134 | 0.97 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL710820 | 0.95 | LMNA (0.56) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL2518118 | 0.92 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL15023824 | 0.92 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL8781961 | 0.92 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL18577736 | 0.92 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL8008849 | 0.92 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL119165 | 0.92 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL125056 | 0.92 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL11084143 | 0.92 | LMNA (0.59) | LMNACA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602685-B1 | Pressing granulated fire retardant composition | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2011-02-02 | — | — | EP | claimed |
| US-20050272839-A1 | Compression-granulated flame retardant composition | CLARIANT GMBH | 2005-12-08 | — | — | US | claimed |
| US-8889772-B2 | Method for producing mixtures of alkylphosphonous acid salts and dialkylphosphinic acid salts | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-11-18 | — | — | US | disclosed |
| US-20130126805-A1 | Method For Producing Alkylphosphonous Acid Salts | CLARIANT FINANCE (BVI) LIMITED (VG) | 2013-05-23 | — | — | US | disclosed |
| US-20130131239-A1 | Method for Producing Mixtures of Alkylphosphonous Acid Salts And Dialkylphosphinic Acid Salts | CLARIANT FINANCE (BVI) LIMITED (VG) | 2013-05-23 | — | — | US | disclosed |
| US-7635785-B2 | Process for preparation of dialkylphosphinic salts | Clariant Deutschland GmbH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7622517-B2 | flame retardant formulation for cellulose-containing moldings ( paperboard, textile, wood), comprising dicyandiamide-formaldehyde resin and a diphoshinic salt of a metal selected from Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Ce, Bi, Sr, Mn, Li | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2009-11-24 | — | — | US | disclosed |
| EP-1705220-B1 | Phosphorous containing heat stabilized fire retardant agglomerates | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2009-10-28 | — | — | EP | disclosed |
| EP-1832595-B1 | Compounds of mono-carboxyl functionalised dialkylphosphine acid salts and other components, a method for their manufacture and their application | CLARIANT FINANCE BVI LTD (VG) | 2009-07-15 | — | — | EP | disclosed |
| US-20090005471-A1 | Phosphorus-containing flame retardant formulation for cellulose-containing moldings | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH | 2009-01-01 | — | — | US | disclosed |
| US-20080241529-A1 | Flameproofed adhesive and sealing materials | CLARIANT INTERNATIONAL LTD. | 2008-10-02 | — | — | US | disclosed |
| EP-1710275-A1 | Stabilized fire retardant | Clariant Produkte (Deutschland) GmbH (DE) | 2006-10-11 | — | — | EP | disclosed |
| US-20060214144-A1 | Phosphorus-containing thermally stabilized flame retardant agglomerates | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH | 2006-09-28 | — | — | US | disclosed |
| US-20060217469-A1 | Use of stabilizers in phosphorus-containing thermally stabilized flame retardant agglomerates | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH | 2006-09-28 | — | — | US | disclosed |
| EP-1705220-A1 | Phosphorous containing heat stabilized fire retardant agglomerates | Clariant Produkte (Deutschland) GmbH (DE) | 2006-09-27 | — | — | EP | disclosed |
| US-20050272839-A1 | Compression-granulated flame retardant composition | CLARIANT GMBH | 2005-12-08 | — | — | US | disclosed |
| US-20050222309-A1 | Phosphorus-containing flame retardant formulation for cellulose-containing moldings | CLARIANT GMBH | 2005-10-06 | — | — | US | disclosed |
| US-20050143503-A1 | Phosphorus-containing flame retardant agglomerates | CLARIANT GMBH | 2005-06-30 | — | — | US | disclosed |
| US-20050137418-A1 | Process for preparation of dialkylphosphinic salts | CLARIANT GMBH | 2005-06-23 | — | — | US | disclosed |
| EP-1544205-A1 | Process for the preparation of dialkylphosphinic acid salts | Clariant GmbH (DE) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130126805-A1 | Method For Producing Alkylphosphonous Acid Salts | AGPAT2, AGPAT5, POF1B | PTGS1 1992/4885MEN1 1716/4885ESR1 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.