Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184745 | 0.92 | DRD2 (0.51) | MAPTDRD2ADRA1ADRD3LMNA | |
| SCHEMBL11167746 | 0.91 | MAPT (0.55) | MAPTDRD2ADRA1ADRD3LMNA | |
| SCHEMBL11163271 | 0.90 | HTR1A (0.52) | MAPTDRD2ADRA1ADRD3LMNA | |
| SCHEMBL11171069 | 0.90 | QPCT (0.52) | MAPTDRD2ADRA1ADRD3LMNA | |
| SCHEMBL11172796 | 0.89 | HTR2A (0.57) | L3MBTL1MAPTTHRBDRD2ADRA1A | |
| SCHEMBL9559731 | 0.84 | THRB (0.59) | L3MBTL1MAPTTHRBDRD2DRD3 | |
| SCHEMBL11170034 | 0.82 | HTR2A (0.57) | MAPTDRD2LMNACACNA1GKCNH2 | |
| SCHEMBL11164429 | 0.80 | LMNA (0.59) | L3MBTL1MAPTDRD2DRD3LMNA | |
| SCHEMBL5654244 | 0.80 | L3MBTL1 (0.75) | L3MBTL1MAPTTHRBDRD2ADRA1A | |
| SCHEMBL11165829 | 0.80 | DRD2 (0.62) | MAPTDRD2LMNAUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420478-A | ANTIBIOTICS, BACTERICIDES, CEPHALOSPORINS | ROUSSEL UCLAF (FR) | 1983-12-13 | — | — | US | claimed |
| US-4413006-A | N-Aryl-N-phenoxy-alkyl-piperazine compounds useful in decreasing intracranial pressure | TANABE SEIYAKU CO., LTD. (JP) | 1983-11-01 | — | — | US | disclosed |
| EP-0034284-B1 | PIPERAZINE DERIVATIVE, PROCESSES FOR PREPARING THE SAME AND THERAPEUTIC COMPOSITIONS CONTAINING IT | Tanabe Seiyaku Co., Ltd. (JP) | 1983-10-05 | — | — | EP | disclosed |
| EP-0034284-A2 | Piperazine derivative, processes for preparing the same and therapeutic compositions containing it | Tanabe Seiyaku Co., Ltd. (JP) | 1981-08-26 | — | — | EP | disclosed |