Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196110 | 0.84 | ALDH1A1 (0.50) | MEN1KMT2AGAATSHRMAPK1 | |
| SCHEMBL11194501 | 0.84 | LMNA (0.51) | MEN1KMT2AGAATSHRMAPK1 | |
| SCHEMBL11197047 | 0.82 | KDM4E (0.52) | GAAMAPK1 | |
| SCHEMBL10856538 | 0.81 | GAA (0.58) | MEN1KMT2AGAATSHRMAPK1 | |
| SCHEMBL10851723 | 0.80 | TNKS (0.50) | MEN1KMT2AGAATSHRMAPK1 | |
| SCHEMBL16825853 | 0.80 | TSHR (0.56) | HRH3MEN1KMT2AGAATSHR | |
| SCHEMBL11201299 | 0.79 | USP2 (0.50) | HRH3MEN1KMT2AGAATSHR | |
| SCHEMBL10860653 | 0.79 | SIGMAR1 (0.54) | MEN1KMT2AGAATSHRHTT | |
| SCHEMBL1045364 | 0.78 | HRH3 (0.67) | HRH3TSHRS1PR4S1PR1S1PR3 | |
| SCHEMBL28144854 | 0.77 | HRH3 (0.47) | HRH3MEN1KMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |