Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194501 | 0.85 | LMNA (0.51) | USP2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11196110 | 0.83 | ALDH1A1 (0.50) | TSHRMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11197047 | 0.83 | KDM4E (0.52) | KCNH2ARMAPK1GAAOPRM1 | |
| SCHEMBL10856538 | 0.82 | GAA (0.58) | USP2TSHRMEN1KMT2AATM | |
| SCHEMBL10851723 | 0.81 | TNKS (0.50) | TSHRCYP2D6MEN1KMT2ACYP2C9 | |
| SCHEMBL10860653 | 0.80 | SIGMAR1 (0.54) | TSHRSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL16825711 | 0.80 | USP2 (0.47) | USP2KCNH2ARTSHRSMN1; SMN2 | |
| SCHEMBL11197942 | 0.79 | HRH3 (0.45) | TSHRSMN1; SMN2MEN1KMT2AHRH3 | |
| SCHEMBL20804360 | 0.77 | KCNJ1 (0.66) | USP2KCNH2TSHRSMN1; SMN2CYP2D6 | |
| SCHEMBL28024576 | 0.77 | KCNJ1 (0.66) | USP2KCNH2TSHRSMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |